Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Mancuso, V.A.; Hope, T.J.; Zhu, L.; Derse, D.; Phillips, T.; Parslow, T.G.

Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

1994

By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

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Mots clés AGROVOC

amino acid sequences binding proteins genetics messenger rna pharmacology recombinant proteins replication rev viral proteins

Informations bibliographiques

Publié dans

Journal of virology

Volume 68 Numéro 3 Pagination 1998 - 2001 ISSN 0022-538X

D'autres materias

Dna mutational analysis; Post-transcriptional; Rna processing; Sequence homology; Amino acid; Molecular sequence data; Amino acid sequence; Equine infectious anemia virus; Immunodeficiency virus; Feline; Structure-activity relationship; Gene products; Drug effects; Infectious anemia virus; Equine; Feline immunodeficiency virus

Langue

anglais

Type

Text; Journal Article

Sur AGRIS depuis: 2024-02-28

Format: MODS

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