Bioactive flavonoids from Knema elegans
2021
Zhang, You-Xi | Lu, Zhao | Wu, Wen-Chao | Chen, Ye-Gao | Zhan, Rui
The twigs and leaves of Knema elegans were analyzed to detect bioactive secondary metabolites. Thirteen flavonoids, including two new compounds (1 and 2), were isolated and characterized. Compounds 1-3, 12, and 13 showed moderate inhibitory effects against α-glycosidase, with IC₅₀ values ranging from 11.80 to 15.77 μM. Moreover, compounds 1, 2, 4, 7, 11, and 13 exhibited radical scavenging capacities in the DPPH and APTS models.
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