Different hypercholesterolemic effects of cholesterol and saturated fat on neonatal and adult chicks
1994
Castillo, M. | Hortal, J.H. | Aguilera, J.A. | Zafra, M.F. | Garcia-Peregrin, E.
Supplementation of 2% cholesterol to the diet produced a significant hypercholesterolemia in adult chicks after 3 days of treatment. The amounts of both free and esterified cholesterol were about 3-fold in cholesterol fed chicks than those found in control animals. In newborn chicks, a significant hypercholesterolemia was observed only after 15 days of the same treatment. Only esterified cholesterol was increased in these conditions. Coconut oil (10 or 20%) supplementation to the diet produced a significant increase of plasma total cholesterol levels after 7 days of treatment of newborn chicks. Both free and esterified forms resulted increased in these conditions. A significant increase of plasma triacylglycerol content was observed 14 days after 20% coconut oil feeding. Contrary to that observed after cholesterol feeding, the hypercholesterolemic effect of coconut oil was not accompanied by changes in the levels of liver cholesterol.
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