Comparative study of the virulence of 3 major Korean porcine circovirus type 2 genotypes (a, b, and d)
2020
Cho, Hyejean | Kang, Ikaje | Oh, Taehwan | Yang, Siyeon | Park, Kee Hwan | Min, Kyung-Duk | Ham, Hee Jin | Chae, Chanhee
The objective of this study was to compare the virulence of 3 major Korean porcine circovirus type 2 (PCV2) genotypes in terms of clinical signs, PCV2 viremia and antibody titers, lymphoid lesions, and PCV2-antigen within lymphoid lesions in experimentally infected pigs. Pigs were infected at 7 weeks with PCV2a, PCV2b, and PCV2d strains and necropsied at 28 days post-infection. No statistical differences were observed in clinical signs, PCV2 viremia and antibody titers, lymphoid lesions scores, and numbers of PCV2 antigens among the 3 major Korean PCV2 genotypes. The results of this study indicate that the 3 major Korean PCV2 genotypes, PCV2a, PCV2b, and PCV2d, have similar virulence.
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