A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation
2010
Stanley, C. E. | Elvira, K. S. | Niu, X. Z. | Gee, A. D. | Ces, O. | Edel, J. B. | deMello, A. J.
We present a simple, automated method for high-throughput formation of droplet interface bilayers (DIBs) in a microfluidic device. We can form complex DIB networks that are able to fill predefined three dimensional architectures. Moreover, we demonstrate the flexibility of the system by using a variety of lipids including 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).
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