Placental growth, development, and function in relation to maternal nutrition
1980
Rosso, P.
Effects of maternal malnutrition on human placental function include reduced mass, size, DNA content and villous capillary surface as well as metabolic changes and changes in composition. Higher levels of alkaline ribonuclease activity correlate wtih degree of maternal malnutrition. Although the physiological implications of these changes are not completely understood, they may suggest impairment of normal placental endocrine function and maternal fetal nutrient exchange, with related effects on fetal growth and development. A comparison is made with data describing placental functions in the malnourished rats. The reduced rate of nutrient transfer in malnourished women and its retarding effects on the fetus may be due to reduced placental blood flow.
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