Effect of dietary egg on variability of plasma cholesterol levels and lipoprotein cholesterol
1985
Oh, S.Y. | Miller, L.T.
Extract: The effects of dietary cholesterol on plasma cholesterol levels, its distribution among lipoproteins, and apoproteins of high-density lipoprotein subclasses in individuals who did and did not demonstrate response in plasma cholesterol levels were studies in 21 healthy middle-aged men for 3 mo. After consumption of 3 eggs/day in addition to their habitual diets for 28 days, 21 subjects were divided into 8 hyper- and 13 hypo-responders. The average plasma cholesterol level of the 21 subjects was changed from 188 to 199 mg/100 ml over the 28-day classification period. During the same period the mean plasma cholesterol level of the hyper-responders was significantly increased from 170 to 199 mg/100 ml while that of the hypo-responders fell slightly. The addition of six eggs to the daily diet of the hypo-responders did not alter the mean plasma cholesterol level but resulted in a wide difference in response of plasma cholesterol concentration. The 13 hypo-responders were divided into hypo-hyper-responders and hypo-hypo-responsers depending upon the degree of change in plasma cholesterol level. The present study illustrated the variabilities of plasma cholesterol level among free-living subjects who demonstrated two-stage thresholds of response to dietary intake of cholesterol. (author)
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