Be sustainable: EOSC‐Life recommendations for implementation of FAIR principles in life science data handling
2023
David, Romain | Rybina, Arina | Burel, Jean‐marie | Heriche, Jean‐karim | Audergon, Pauline | Boiten, Jan‐willem | Coppens, Frederik | Crockett, Sara | Exter, Katrina | Fahrner, Sven | Fratelli, Maddalena | Goble, Carole | Gormanns, Philipp | Grantner, Tobias | Grüning, Björn | Gurwitz, Kim Tamara | Hancock, John | Harmse, Henriette | Holub, Petr | Juty, Nick | Karnbach, Geoffrey | Karoune, Emma | Keppler, Antje | Klemeier, Jessica | Lancelotti, Carla | Legras, Jean‐luc | Lister, Allyson | Longo, Dario Livio | Ludwig, Rebecca | Madon, Bénédicte | Massimi, Marzia | Matser, Vera | Matteoni, Rafaele | Mayrhofer, Michaela Th | Ohmann, Christian | Panagiotopoulou, Maria | Parkinson, Helen | Perseil, Isabelle | Pfander, Claudia | Pieruschka, Roland | Raess, Michael | Rauber, Andreas | Richard, Audrey | Romano, Paolo | Rosato, Antonio | Sánchez-Pla, Alex | Sansone, Susanna‐assunta | Sarkans, Ugis | Serrano-Solano, Beatriz | Tang, Jing | Tanoli, Ziaurrehman | Tedds, Jonathan | Wagener, Harald | Weise, Martin | Westerhoff, Hans | Wittner, Rudolf | Ewbank, Jonathan | Blomberg, Niklas | Gribbon, Philip | European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL) | European Molecular Biology Laboratory (EMBL) | Euro-BioImaging ERIC Bio-Hub (Euro-BioImaging) | University of Dundee | European Molecular Biology Laboratory [Heidelberg] (EMBL) | INSTRUCT ERIC | European Advanced Translational Research Infrastructure (EATRIS) | Center for Plant Systems Biology (PSB Center) ; Vlaams Instituut voor Biotechnologie [Ghent, Belgique] (VIB) | European research infrastructure for biobanking (BBMRI-ERIC) | Flanders Marine Institute (VLIZ) | Forschungszentrum Jülich GmbH | Centre de recherche de Jülich | Jülich Research Centre (FZJ) ; Helmholtz-Gemeinschaft = Helmholtz Association | Istituto di Ricerche Farmacologiche "Mario Negri" = Mario Negri Institute for Pharmacological Research (IRCCS) | University of Manchester [Manchester] | INFRAFRONTIER GmbH [Neuherberg] | Vienna University of Technology = Technische Universität Wien (TU Wien) | Albert-Ludwigs-Universität Freiburg = University of Freiburg | Univ West England, Dept Appl Sci, Bristol BS16 1QY, Avon, England | European Bioinformatics Institute [Hinxton] (EMBL-EBI) ; EMBL Heidelberg | ELIXIR Hub [Cambridge] | Fakultät für Mathematik und Geoinformation [Wien] (TU Wien) ; Vienna University of Technology = Technische Universität Wien (TU Wien) | Historic England | Universitat Pompeu Fabra [Barcelona] (UPF) | Sciences Pour l'Oenologie (SPO) ; Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier ; Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM) | University of Oxford | Consiglio Nazionale delle Ricerche [Bologna] (CNR) | Universidad de Sevilla = University of Seville | National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR) | The Alan Turing Institute | European Clinical Research Infrastructures Network [Dusseldorf] (ECRIN) | EMBL Heidelberg | Institut National de la Santé et de la Recherche Médicale (INSERM) | Institute of Bio- and Geosciences [Jülich] (IBG) ; Forschungszentrum Jülich GmbH | Centre de recherche de Jülich | Jülich Research Centre (FZJ) ; Helmholtz-Gemeinschaft = Helmholtz Association-Helmholtz-Gemeinschaft = Helmholtz Association | IRCCS Ospedale Pediatrico Bambino Gesù = Bambino Gesù Children’s Hospital | Università degli Studi di Padova = University of Padua (Unipd) | Veneto Institute of Oncology IOV-IRCCS [Padua, Italy] | Instituto de Salud Carlos III [Madrid] (ISCIII) | Universitat de Barcelona (UB) | Oxford e-Research Centre [Oxford] ; University of Oxford | European Molecular Biology Laboratory [Hinxton] | Pennsylvania State University (Penn State) ; Penn State System | Center for Permafrost (CENPERM) ; Department of Geosciences and Natural Resource Management [Copenhagen] (IGN) ; Faculty of Science [Copenhagen] ; University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH)-Faculty of Science [Copenhagen] ; University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH) | Department of Physical Geography and Ecosystem Science [Lund] ; Skane University Hospital [Lund] | University of Copenhagen = Københavns Universitet (UCPH) | Department of Molecular Cell Physiology [VU Amsterdam] ; Vrije Universiteit Amsterdam [Amsterdam] (VU) | This research is mainly a product of the EOSC-Life European programme funding from the European Union's Horizon Europe research and innovation programme under grant agreement Nº824087. Complementary support was provided through EU funded project AgroServ (grant agreement Nº101058020), EU funded project BY-COVID (grant agreement Nº101046203), EU funded project DANUBIUS-IP (grant agreement Nº101079778), EU funded project EMPHASIS-GO (grant agreement Nº101079772), EU funded project FAIRplus (IMI grant agreement Nº802750), EU funded project FAIRsharing (Wellcome grant agreement Nº212930/Z/18/Z), EU funded project ISIDORe (grant agreement Nº101046133), EU funded project Precision Toxicology (grant agreement Nº965406), UKRI DASH (grant agreement NºMR/V038966/1). Special thanks to T. Biro and her radical collaboration team from Research Data Alliance who gave us great inspiration on how to lead this radical collaboration work. | European Project: 824087,H2020-INFRAEOSC-2018-2020,H2020-INFRAEOSC-2018-2,EOSC-Life(2019) | European Project: 101046203,HORIZON-INFRA-2021-EMERGENCY-01,HORIZON-INFRA-2021-EMERGENCY-01,BY-COVID(2021) | European Project: 101079778,HORIZON-INFRA-2021-DEV-02,HORIZON-INFRA-2021-DEV-02,DANUBIUS IP(2022) | European Project: 101079772,HORIZON-INFRA-2021-DEV-02,HORIZON-INFRA-2021-DEV-02,EMPHASIS-GO(2022) | European Project: 101046133,HORIZON-INFRA-2021-EMERGENCY-02,HORIZON-INFRA-2021-EMERGENCY-02,ISIDORe(2022)
International audience
Afficher plus [+] Moins [-]anglais. The main goals and challenges for the life science communities in the Open Science framework are to increase reuse and sustainability of data resources, software tools, and workflows, especially in large‐scale data‐driven research and computational analyses. Here, we present key findings, procedures, effective measures and recommendations for generating and establishing sustainable life science resources based on the collaborative, cross‐disciplinary work done within the EOSC‐Life (European Open Science Cloud for Life Sciences) consortium. Bringing together 13 European life science research infrastructures, it has laid the foundation for an open, digital space to support biological and medical research. Using lessons learned from 27 selected projects, we describe the organisational, technical, financial and legal/ethical challenges that represent the main barriers to sustainability in the life sciences. We show how EOSC‐Life provides a model for sustainable data management according to FAIR (findability, accessibility, interoperability, and reusability) principles, including solutions for sensitive‐ and industry‐related resources, by means of cross‐disciplinary training and best practices sharing. Finally, we illustrate how data harmonisation and collaborative work facilitate interoperability of tools, data, solutions and lead to a better understanding of concepts, semantics and functionalities in the life sciences.
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