Chemistry of the fumiquinazolines and structurally related alkaloids
2019
Resende, D.I.S.P | Boonpothong, P | Sousa, E | Kijjoa, A | Pinto M.M.M. | Centro Interdisciplinar de Investigação Marinha e Ambiental
Covering: this review covers the literature from 1992 to 2018 To date, approximately 80 naturally-occurring secondary metabolites which are structurally-related to fumiquinazolines have been isolated, mainly from marine sources. These alkaloids can be classified into twelve different groups and exhibit different structure motifs depending on the amino acids from which they are derived. This review is focused on isolation, structure elucidation, biological activities, biosynthetic pathways, and synthetic studies of these natural products. © 2019 The Royal Society of Chemistry.
Afficher plus [+] Moins [-]This work was partially supported through national funds provided by FCT/MCTES – Foundation for Science and Technology from the Minister of Science, Technology and Higher Education (PIDDAC) and European Regional Development Fund (ERDF) through the COMPETE – Programa Operacional Factores de Competitividade (POFC) programme, under the Strategic Funding UID/Multi/04423/2013, the project POCI-01-0145-FEDER-028736 and PTDC/MAR-BIO/4694/2014 (reference POCI-01-0145-FEDER-016790; Project 3599 – Promover a Produção Científica e Desenvolvimento Tecnológico e a Constituição de Redes Temáticas (3599-PPCDT)) in the framework of the programme PT2020 as well as by the project INNOVMAR – Innovation and Sustainability in the Management and Exploitation of Marine Resources (reference NORTE-01-0145-FEDER-000035, within Research Line NOVELMAR), supported by North Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). Papichaya Boonpothong (ALFABET Scholarship) and Diana I. S. P. Resende (NOVELMAR/BPD_2/2016-019) also acknowledge for their grants.
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