Pre-administration of vitamin C reduces exercise-induced oxidative stress in untrained subjects
2014
Trofin Florin-Petrut | Chirazi Marin | Honceriu Cezar | Drosescu Paula | Grădinariu Gabriela | Vorniceanu Alin | Anton Emil | Cojocaru Dumitru | Ciobica Alin | Ciornea Elena | Cojocaru Ioana Sabina
We investigated the effects of a 40 min bout of bicycle exercise, and the effects of vitamin C administration 12 h before exercise, on the serum markers of oxidative stress in young untrained subjects. Increased levels of malondialdehyde, the marker of the lipid peroxidation, and a decrease in specific activity of the antioxidant enzyme glutathione peroxidase that were observed as a result of exercise, pointed to the presence of exercise-induced oxidative stress. These markers were reduced by pre-administration of vitamin C. The results suggest that physically active subjects could increase their daily dietary vitamin C intake in order to reinforce their antioxidant defenses prior to exercise training.
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