Skin T cells maintain their diversity and functionality in the elderly
2021
Hanako Koguchi-Yoshioka | Elena Hoffer | Stanley Cheuk | Yutaka Matsumura | Sa Vo | Petra Kjellman | Lucian Grema | Yosuke Ishitsuka | Yoshiyuki Nakamura | Naoko Okiyama | Yasuhiro Fujisawa | Manabu Fujimoto | Liv Eidsmo | Rachael A. Clark | Rei Watanabe
Koguchi-Yoshioka et al. demonstrate that functional activities and diversity of T cells are highly maintained in the skin of elderly people when compared with those in the blood regardless of the ethnicity of the participants or the experimental procedures. They also find the accumulation of epidermal T cells with maintained cytokine production in the elderly participants.
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