Ecotoxicological assessment of TiO2 byproducts on the earthworm Eisenia fetida
2011
Bigorgne, Emilie | Foucaud, Laurent | Emmanuel, Lapied | Labille, Jérôme | Botta, Céline | Sirguey, Catherine | Falla, Jaïro | Rose, Jérôme | Joner, Erik J. | Rodius, François | Nahmani, Johanne | Laboratoire des Interactions Ecotoxicologie, Biodiversité, Ecosystèmes (LIEBE) ; Université Paul Verlaine - Metz (UPVM)-Centre National de la Recherche Scientifique (CNRS) | Bioforsk Soil and Environment | Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement (CEREGE) ; Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS) | International Consortium for the Environmental Implications of Nanotechnology (iCEINT), Aix en Provence, France | Laboratoire Sols et Environnement (LSE) ; Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL) | French Environment and Energy Management Agency (ADEME); Region Lorraine
International audience
Afficher plus [+] Moins [-]anglais. The increasing production of nanomaterials will in turn increase the release of nanosized byproducts to the environment. The aim of this study was to evaluate the behaviour, uptake and ecotoxicity of TiO2 byproducts in the earthworm Eisenia fetida. Worms were exposed to suspensions containing 0.1, 1 and 10 mg/L of byproducts for 24 h. Size of TiO2 byproducts showed aggregation of particles up to 700 mu m with laser diffraction. Only worms exposed at 10 mg/L showed bioaccumulation of titanium (ICP-AES), increasing expression of metallothionein and superoxide dismutase mRNA (Real-time PCR) and induction of apoptotic activity (Apostain and TUNEL). TiO2 byproducts did not induce cytotoxicity on ccelomocytes, but a significant decrease of phagocytosis was observed starting from 0.1 mg/L In conclusion, bioaccumulation of byproducts and their production of reactive oxygen species could be responsible for the alteration of the antioxidant system in worms. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.
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