On the Current Situation of Glanders in Various Districts of the Pakistani Punjab
2012
Khan, Iahtasham | Wieler, L.H. | Butt, M.A. | Elschner, Mandy C. | Cheema, A.H. | Sprague, Lisa D. | Neubauer, Heinrich Karl Johann
Glanders is a highly infectious and zoonotic disease of solipeds caused by Burkholderia mallei. Progressive loss of efficiency and fatal outcome resulted in massive economic losses, which forced veterinary authorities throughout the world to implement disease control measures; these measures included mass testing using the complement fixation test and/or malleinization, and the culling of positives. This led to the eradication of glanders from Western Europe and North America in the 1950s. However, in the last decade, the number of outbreaks in Asia and South America increased steadily, and glanders regained the status of a re-emerging transboundary disease. Pakistan has been an endemic country for the past 120 years, but concise data on the presence of disease are not available. A total of 533 serum samples were collected from draught equines, a suspected risk group for glanders, from various districts of Punjab in Pakistan. The complement fixation test and the highly sensitive Western blot technique were used for serodiagnosis. No animal (horse, mule, and donkey) was found to be positive for infection. Glanders seems to be restricted to remote, sporadic pockets of endemicity and may cause outbreaks after being introduced into naive populations by (asymptomatic) shedders.
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Editeur Elsevier Science
ISSN 1542-7412 | 0737-0806Cette notice bibliographique a été fournie par Friedrich-Loeffler-Institut
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