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Advancing the science of developmental neurotoxicity (DNT): Testing for better safety evaluation

2012

Bal-Price,A.K. | Coecke,S. | Costa,L. | Crofton,K.M. | Fritsche,E. | Goldberg,A. | Grandjean,P. | Lein,P.J. | Li,A. | Lucchini,R. | Mundy,W.R. | Padilla,S. | Persico,A.M. | Seiler,A.E.M. | Kreysa,J.

Mots clés AGROVOC
algorithms alternative methods analysis animal testing alternatives animals apoptosis arrays assessment association biology blood brain calcium california cancer cell culture cell differentiation cells cells central nervous system chemicals children congresses consumer protection danio rerio development diagnostic drugs effects environmental protection epidemiology epigenomics evaluation fibroblasts form france gene gene expression gene expression regulation genes growth guidelines health health risks hormone humans in vitro industry inhibition italy lead legislation liver mammals methods migration model models nervous system neurotoxicity oecd origin pah pcb pesticide pesticides poisoning pollution polychlorinated biphenyls pregnancy protection protein proteins rat reproducibility research risk risk assessment safety science screening sera serine signal spectra spectrum state strategies substances system systems technology testing tests tissue toxicity toxicity tests toxicology trends
Informations bibliographiques
Volume 29 Numéro 2 Pagination 202 - 215

Editeur Springer Spektrum

ISSN 1868-596X | 1868-8551
D'autres materias
Note; Cell-cultures; Developmental disorder; Embryotoxicity test; Tissues; Alternative method; Polybrominated diphenyl ether; Environmental chemical; Neurite outgrowth; Article; Pahs; Developmental; Cultured; In vitro test; Toxicity testing; Exposure; Comparison; Studies; Reference; Neurotoxicity syndromes; Culture; Cyp1a1; Activation; Guideline; Mouse; Endocrine; Developmental neurotoxicity; Quantitation; Species specificity; Regulation; Embryo; Biphenyls; Predict; Risk-assessment; Target; Hazardous substances; Health effects; Line; Polychlorinated-biphenyls; Induce; Environmental chemicals; Drug; Thyroid-hormone; Gene-expression; Health risk assessment; Mechanisms; Stem cells; Project; Acute; Chemical substance; Chemical-substances; Cell line; Conference paper; Tcdd; Neurology; Study; Animal testing alternative; Conference; Issues; Response; Changes; Drug; Biomarker; Searching; Reliability; Prevention; Differentiation; Endpoints; Sensitivity; Toxic; Male; Validation; Nonhuman; Genomic; Vivo; United states; Chemical; Vitro; Assay; Growth-factor; United-states; Phenotype; Insights; In-vitro; Disease; Review; Child; In-vivo; Cultures; Cell; Pathways; Biomarkers; In vivo; Effect; Signal transduction; Human; In-utero; Health risk; Danio; Framework; Environmental; Neurons; Hazard; Serum; Prevalence; Recommendations; Targets; Congresses as topic; Mechanism; Strategy; Safety evaluation; Embryonic stem cells; Molecular mechanisms; Report; Zebrafish; Endocrine disruption; Origins; Parkinson's disease; Danio-rerio; Physiological; Responses; Embryonic stem cell test; Test guideline; Potential; Adverse effects; Pathway; Impact; Comparative; Embryotoxicity; Industrial chemicals; Method; Number; Long-term; Alternative; Control; In vitro tests; International; Neurologic examination; Occupational-exposure; Thyroid hormone receptors; Performance; Embryonic stem cell; Cell-line; High throughput screening; Approach; German; Technologies; Consumer; Expression; Reproductive toxicity; Proliferation; Establishment; Growth factor; Transgenic; Investigation; Central-nervous-system; Detect; Occupational exposure
Langue
anglais
Type
Journal Article; Text
2025-02-03
2025-10-25
MODS
Fournisseur de données

Cette notice bibliographique a été fournie par German Federal Institute for Risk Assessment

Découvrez la collection de ce fournisseur de données dans AGRIS

Liens
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