Açlığın Beyin Korteksinin Farklı Bölgelerindeki Nötral Peptid Hidrolazların Aktifl iği Üzerine Etkisi
2019
Temur, A. | Askerov, F. | Temur, H. B. | Karadağ, H.
The present study was designed to determine the activity of the neutral peptide hydrolase (NPH) in the Sensorimotor (SC), Limbic (LC) and Orbital (OC)cortexes of the brain at some periods of starvation. Furthermore, histochemical investigation was also made in these cortexes. The study was performed ineighty Wistar-Albino rats. The rats were subjected to starvation for the periods of 1, 3 and 5 days. The activity of the NPH was biochemically determined inthe sensorimotor, limbic and orbital cortexes. It was concluded that while the neurons of the brain cortex responded to the organism-related food motivationimpulses at the beginning of starvation, later on the neurons tried to adapt to the food lack for protein renovation.
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