Derivation of human-derived iPSC line from a male adolescent with first-episode of sporadic schizophrenia
2025
Youhui Jiang | Chuqing Zhou | Jun Zhao | Xinyi Ren | Qiang Wang | Peiyan Ni | Tao Li
Schizophrenia is considered to be a neurodevelopmental disorder with high heritability. In this study, peripheral blood mononuclear cells (PBMCs) were collected from a male adolescent diagnosed with first-episode of sporadic schizophrenia. Induced pluripotent stem cells (iPSCs) were generated by reprogramming using the factors OCT4, SOX2, NANOG, LIN28, c-MYC, KLF4, and SV40LT. The generated iPSC line was validated by karyotype analysis and expression of pluripotency markers. These iPSCs were capable of differentiating into derivatives of all three germ layers in vivo.
Afficher plus [+] Moins [-]Mots clés AGROVOC
Informations bibliographiques
Cette notice bibliographique a été fournie par Directory of Open Access Journals
Découvrez la collection de ce fournisseur de données dans AGRIS