EFFECT OF Salvia officinalis and Thyme Vulgaris OIL ON HEMATOLOGICAL PARAMETERS OF INDUCED GASTRIC ULCER IN MATURE FEMALE RATS

The present study has been carried out at the department of physiology, Collegeof Veterinary Medicine of Basrah, to evaluate the role of oil extracted from salviaofficinalis and Thymus vulgaris leaves in some structural and functionalcharacteristics of mature female rats experimentally induced with gastriculcer.Oils of thyme and sage were extracted from dry leaves available in Basrahmarket by normal hexane, oils components have been analyzed in a manner GCMAS (Gas chromatography). Gastric ulcers were induced in starved female rats bygiving indomethacin orally by mouth gavage in a dose 25mg\kg for one day. Theanimals have been divided into seven equal groups(8 females in each group). Thefirst group was received normal saline and served as a negative control. Secondgroup serve as positive group that received only single dose of indomethacin,whereas third group treated with thyme crude oil for two week ,fourth group thattreated with thyme dilution oil for two weeks,fifth group treated with sage crudeoil for two week, sixth group treated with sage dilution oil for two weeks andseventh group treated with cimetidine for two weeks. The blood has been obtainedfor hematological assessment the present results: showed no changed in RBCs ,PCV of female rats groups treated with thyme crude,thyme dilution, sage crudeoil and cimetidine and just group treated with sage dilution caused a significant decrease in RBCs and PCV among treated group. So, the results revealed thatthere is no- changed in WBC in groups treated with thyme crude, thyme dilutionand sage dilution ,whereas showed a decreased in gastric ulcer group, sage crudeand cimetidine group. Also neutrophils existed increase significantly in all treatedgroups compared with control negative group ,whereas no change recorded inthyme dilution and sage crude groups compared with control negative group