The Influence of Maternal Nutrition on the Lifetime Performance of Nellore Cattle Offspring

Fetal programming suggests that maternal nutrition during gestation influences offspring growth, development, and productivity. This study evaluated the effects of prenatal protein-energy supplementation on the lifetime performance of Nellore cattle. Twenty-eight nulliparous heifers were inseminated and assigned to one of two groups: Non-Programmed; receiving only mineral supplementation; or Fetal Programmed (FP); receiving additional protein-energy supplementation throughout gestation. Cows in the FP group maintained significantly better body condition score during gestation (<i>p</i> < 0.01), and their calves exhibited greater body weight (BW) during the first 56 days (<i>p</i> < 0.05) and a tendency to grow to a greater BW up to 250 days (<i>p</i> < 0.10) in addition to improved morphological traits, such as increased rump width and length at 45 days of age (<i>p</i> ≤ 0.02). However, these advantages were not sustained in later growth stages, as no significant differences were observed in final body weight, ultrasound carcass traits, or overall feedlot performance. These findings suggest that while prenatal nutrition can influence early developmental traits, its long-term impact on offspring performance may be limited under consistent postnatal management. Nonetheless, the limited sample size, combined with the absence of molecular data and individual feed intake and efficiency measurements, constrains a more comprehensive interpretation of the programming effects on offspring performance. Further research is needed to explore the molecular mechanisms of fetal programming, particularly its epigenetic effects and interactions with postnatal nutrition, to optimize strategies for improving the efficiency and sustainability of beef cattle.