Effects of Black ginger (Kaempferia parviflora) on the testicular function in streptozotocin-induced diabetic male rats
2016
Fungfuang, Wirasak | Lert-Amornpat, Teerayuth | Maketon, Chan
The present study aimed to investigate the efficacy of Black ginger (Kaempferia parviflora; KP) on testicular function in streptozotocin (STZ)-induced diabetes rats (DM). Six-week-old male Wistar rats were used in this experiment. All rats were randomly divided into six group; group 1: Normal group, group 2: DM (control), group 3: DM rats received gibencamide 5 mg/kg, group 4-6: DM rats received KP 140, 280 and 420 mg/kg, respectively. DM was induced by intraperitoneal injection of STZ (60 mg/kg). All animals were treated for 6 weeks. Blood glucose, epididymal sperm parameter, testicular microstructure and testosterone level were evaluated. The result showed that KP treatment has no effect on blood glucose in DM rats. KP treatment showed significantly increased sperm density, serum testosterone and ameliorates testicular structure in DM rats (p<0.05). The present study indicates that the aphrodisiac properties of KP could improve of sperm density, testosterone level and testicular function in STZ-induced diabetes rats.
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