Standardized Black Chokeberry (aronia Melanocarpa L.) Extract Supplementation Reduces the Salivary Ros Levels in Oral Lichen Planus Patients
2024
Pirković, A. | Dekanski, D. | Hadži-Mihailović, M. | Stanimirović, D. | Prokić, M. | Bojić-Trbojević, Ž.
The oxidative stress has a role in etiopathogenesis of oral lichen planus (OLP). Polyphenols renowned for their antioxidative, anti-inflammatory and immunomodulatory properties, have gained attention in autoimmune diseases management. Saliva, reflecting salivary gland health, offers promise for biomarker research and treatment monitoring. The aim of this study was to evaluate salivary levels of reactive oxygen species (ROS) in OLP patients using polyphenol rich, standardized Aronia melanocarpa extract (SAE). The ROS values were compared in pre- and post-treatment and significant differences were found, indicating the decrease of ROS after four-week supplementation with SAE.
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Editeur Vinča Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade
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