Relevance. Solanum tuberosum L. – it is one of the main food crops, therefore, the study of the influence of innovative growth regulators on physiological and biochemical parameters and plant yield is very important for the agro-industrial complex.Material and methods. The research was carried out on the gray forest soil of the Orel region in the conditions of a vegetation house on the basis of the farm Stebakov V.I. in the period 2020-2021. Potato of the Nevsky variety was used as the object of the study. Treatment with growth regulators was carried out by soaking Solanum tuberosum tubers in aqueous solutions of melafene (10-6%), Energy-M (10-3%) for 8 hours. When laying the experiments, the optimal amount of nitrogen (2.3 g), phosphorus (0.7 g) and potassium (3.1 g) was introduced into the soil for potato. Was determined catalase, peroxidase activity. The amount of hydroperoxides, an intermediate product of POL, was estimated by reaction with ammonium rhodanide, the content of malonic dialdehyde by reaction with thiobarbituric acid. The experiment was carried out three times. Statistical processing of the results was carried out by the method of one-factor analysis of variance using the computer program "MS Exel".Results. Studies have shown that there is an increase in the activity of catalase and peroxidase in all variants of the experiment compared with the control in leaves, in tubers – the activity of enzymes decreases. There was a decrease in the content of malondialdehyde in all variants of the experiment compared with the control. The analysis of the final productivity revealed that the total number of tubers on one bush of the potato in the variants with growth regulators changes slightly, while the mass of tubers increases, so the variant with the growth regulator melafen increased this indicator by 37% compared to the control.

Relevance. Oxidative reactions (based on peroxidase activity, POX and polyphenol oxidase, PPO; hydrogen peroxide content) that occur in response to infection or reinfection of the off-spring of infected plants depend on the type of host-virus interaction (sensitive, tolerant, stable) and the nature of the interaction with viral infection (primary infection, reinfection of second and third generations).Results. Reinfection with tomato aspermy virus (TАV) or tobacco mosaic virus (TMV) of the off-spring of third infected tomato generation caused a significant decrease in POX activity compared to successive generations of infected plants (G2) for Craigella (Tm-22/Tm- 22) and S. pimpinellifolium genotypes or an increase for Rufina and Craigella (Tm-1/Tm-1) ones. In genotypes containing resistance genes, Rufina and Craigella, no differences were observed in PPO of TMV primary infection and control, while significant differences were found in case of TAV (susceptibility). As a result of TMV infection, the sensitive (Elvira) and tolerant (S. pimpinellifolium) genotypes showed an increase in PPO values compared to the control. At the same time, in most genotypes primarily / secondarily infected with TAV or TMV, statistically significant differences were revealed in the activity of POX or PPO, as well as the accumulation of hydrogen peroxide in plant leaves, which indicates specific protective reactions of the genotypes.