In the Armavir marz of the Republic of Armenia, the effect of the load of buds was studied on the growth, yield, and quality indicators of the Nrneni grape variety. This grape variety was created at the Armenian Agricultural Institute, by crossing the 1-17-1 (Alicant Bushe x Cabernet Sauvignon) hybrid form and the Georgian Saperavi varieties. The Nrneni grape variety is lateripening, moderately high-growing, with low frost resistance and high fungal disease resistance. Experimental vineyards were planted at a planting density of 2.5x1.5 m. The vines were formed according to a low-stem multi-arm fan-shaped formation: The load of the vines was studied at 20, 30, 40, and 50 buds. Research findings related to shoot growth, ripening, and harvest quality enable us to recommend the optimal vine load for the Nrneni grape variety in the Armavir marz region. Based on these studies, we suggest maintaining a load of 30–40 buds per vine.