Toxicology is a science that dates to Ancient Egypt. Animal and herbal poisons were classified according to their source, and cases were categorized based on symptoms, with comments about prognosis, were included at texts were written Ancient Egypt period. In the texts written by the ancient writer Strabo, it is understood that communities with mastery on snakes lived in Anatolia. There is also information that plant-derived poisons were used in hunting and war tools in ancient time. It is seen that poisons were used quite widely in the Roman Period. There is also the extensive use of lead, especially in Roman plumbing, caused researchers to think about whether there was mass chronic poisoning. The aim of this study is to determine the current situation in order to use the Toxicology discipline in the field of Archaeology and to shed light on the period by using animals that met needs such as food sources, mounts and protection in the ancient period as biomarkers.