The increasing number of diseases with urogenital chlamydiosis became a serious problem for the modern veterinary science. The importance of urogenital clamidiosis in the infectious pathology of animals was presented by the direct multifocal affect of urogenital system and after-effects of a disease influencing the reproductive function, as well as the potential hazard of its transformation into a source of chlamydia infections of other localization. In the conditions of the Republic of Belarus the chlamydial endometritis of cattle in the majority of cases was associated with Staphylococcus aureus in 25,7% of cows. Chlamydial endometritis of cows was usually preceded by: embryotocia (9,9%), pathological calving (4,4%), retention of placenta (14,8%), subinvolution of uterus (27,1%). The biochemical tests in trial group showed the 23% decrease of carotin on twofold decrease vitamin A. In course of the immunologic studies it was established, that dilution of A class immunoglobulins was on 31% higher in animals of a trial group in comparison with the control group. The level of IgG immunoglobulin G and immunoglobulin M slightly differed between groups

There were studied the most effective methods of diagnostics of genital forms of clamidiosis at cows in pregnancy, calving and the postnatal period. The description is resulted and the estimation is given methods of laboratory diagnostics, serological methods, a method of light microscopy, immunofluorescence, enzyme immunoassay, chlamydia allocation method on laboratory models, complement linkage reaction, hemagglutination reaction, a method of polymerase chain reaction. As a result of complex use of reaction of complement linkage reaction, on the basis of the analysis of clinical and histologic research, studying of a condition of immune system and nonspecific resistance of an organism it is possible to carry out successfully diagnostics of genital forms of clamidiosis at cows. | Целью исследований явилось изучение наиболее эффективных методов диагностики генитальной формы хламидиоза у коров в период беременности, ca и послеродового периода. Приведено описание и дана оценка методам лабораторной диагностики, серологическим методам, методу световой микроскопии, иммунофлюоресценции, иммуноферментному анализу, методу выделения хламидии на лабораторных моделях, реакции связывания комплемента, реакции гемагглютинации, методу полимеразной цепной реакции. В результате комплексного использования реакции связывания комплемента (РДСК), на основании анализа клинических и гистологических исследований, изучения состояния иммунной системы и неспецифической резистентности организма можно успешно проводить диагностику генитальной формы хламидиоза у коров.