Betamethasone, a fluorinated and synthetic steroid, is a commonly used glucocorticoid. To our knowledge, no available studies exist concerning the hyperlipidemic effect of betamethasone dipropionate (BDP) in rabbits. Therefore, the current study was conducted to highlight the effects of intramuscular injection of BDP on lipid profile in rabbits, investigate the possible mechanism underlying the produced effects and evaluate the possible antihyperlipidemic effect of atorvastatin (ATR) and fenofibrate (FFB). For this purpose, twenty male New Zealand rabbits were classified into control, BDP (0.5 ml/kg B.wt/ IM/day/single dose), BDP+ATR; rabbits were IM injected with BDP, then they were orally given ATR (1.9 mg./kg. B.wt./ once/ day/ month) and group IV (BDP+FFB); rabbits were IM injected with BDP then they were orally given FFB (7.5 mg/kg B.wt/ once/ day/ month). The obtained result revealed that single IM injection of BDP produced a significant elevation in triglycerides, total cholesterol, LDL level with a significant decline in HDL in comparison to control group on the 3rd,7th,14th, 21st, 30th day of the experiment. On the 30th day of the experiment there was an increase in the ALT, AST, MDA, VCAM-1 as well as a significant decrease in TAC. Furthermore, BDP induced a significant increase in HMG-COA reductase gene expression and a significant decrease in lipoprotein lipase gene expression. Oral administration of ATR or FFB concurrently with BDP for a month succeeded in reducing the hyperlipidemia induced by BDP in rabbits.

The study was conducted to find out the effect of age on carcass, meat quality characteristics and nutritional composition of Nandanam Turkey-II. Totally twelve birds were separated into two different age groups viz., young (20 weeks) and adult (40 weeks). The birds were slaughtered and breast muscle was obtained. The carcass, meat quality characters, proximate composition, amino acid, fatty acid and cholesterol content of meat of two age groups were analysed. The carcass characteristics viz., edible offal weight, in-edible offal, blood weight, feather weight and head weight had significant difference (P<0.01) between two age groups. Meat quality characteristics viz., pH (P<0.05), muscle fibre diameter (P<0.01) and myofibrillar fragmentation index (P<0.01) of young turkey meat were significantly lower than adult turkey meat. The young turkey meat had significantly higher moisture content (P<0.01), while it showed significantly lower protein, fat and total ash content than adult turkey meat. The significant difference (P<0.05) was observed in lysine and phenylalanine and highly significant difference (P<0.01) was observed in arginine, isoleucine, threonine, valine, alanine, aspartic acid, glutamic acid and glycine contents of meat from young and adult age groups of turkey. The meat of young turkey had significantly lower total saturated fatty acids (P<0.01), mono unsaturated fatty acids (P<0.05) and higher poly unsaturated fatty acids (P<0.01), P/S ratio when compared to adult turkey meat. The cholesterol content of young turkey meat was significantly (P<0.01) lower than adult turkey meat. Based on the results it was concluded that the meat of young Nandanam Turkey-II had the superior meat quality characters and nutritional composition than the meat of adult birds.