A case was diagnosed as canine multicentric lymphoma based on clinical presentation, FNAC and ultrasonography and was treated with CHOP-19 protocol and remission was observed on 9th week but the protocol was continued up to 19th week and no signs of relapse was noticed. The animal was monitored every month for month after the treatment (19 weeks) animal showed no signs of reoccurrence up to 7 months. Multicentric lymphoma is a disease that the general practitioner can manage; it does not require referral to a specialized practice.

A nine year old non-descript male dog was presented to Madras Veterinary College Teaching Hospital with a history of anorexia, weakness, and clinical signs of respiratory distress and pyrexia. TFAST (thoracic-focused assessment with sonography for trauma) of the lung was performed to rule out pleural effusion. Upon confirmation of pleural effusion, thoracocentesis was performed and sample was collected to identify the cause. The pleural effusion was confirmed as haemothorax and cytology of the sample wasconfirmed as mesothelioma. 

The present study was carried out to find out the histopathological alterations in gill, liver and kidney of Goldfish (Carassius auratus) under sublethal concentrations of Zinc. Fishes were exposed to sub-lethal concentrations of 0.572, 1.145, 2.289, 4.578 and 9.156 mg.l -1 for 28 days which are 1/10 of their 96hr LC. The histological samples of gill, liver and kidney were collected from 14 th, 50th  and 28th day and stained by haematoxylin and eosin, observed under trinocular microscope. Vacuolation, hyperplasia, epithelial lifting and lamellar fusion, shrinkage of blood vessels, secondary lamellar damage, breakdown of epithelial cells, blood congestion and necrosis were observed in gill. Rupture of nucleus, congested blood vessels, hemorrhage in liver sinuses, increased size of kupffer cell, increased pycnotic nucleus, hypertrophied hepatocytes, vacuolation, cellular necrosis, rupture of hepatocytes were observed in liver of zinc treated fish. Shrunken glomerulus, vacuolation, blood congestion, increased in space of periglomerular, increased in space of peritubular, melanomacrophages, loss of cytoplasm, fat deposition, degenerated tubules and degenerated glomerulus were seen in kidney. The above results showed that sub-lethal toxicity of Zinc alter the internal organs of goldfish at lower concentration.

A comparison of milk yield and composition of various indigenous and crossbred cattle was undertaken to evaluate their performance in the subtropical high altitudes of Kerala. A total of 173, 95, 63 and 63 morning milk samples from 42 CBHF, 12 Vechur, six Sahiwaland six Kankrej cows of early second lactation were analyzed for total solids, fat, solids-not-fat, lactose, protein and chloride by conventional  methods. Least squares analysis revealed that breed and test-day climate significantly influenced the milk yield and composition (P >0.05). The mean lactation yield in Vechur, Sahiwal, Kankrej and CBHF were 514.62 ± 42.87 Kg, 1025.65 ± 358.15 Kg, 1102.45 ± 358.15 Kg and 1763.93 ± 128.16 Kg respectively. Kankrej had higher fat and total solids while Vechur had higher SNF, protein and lactose (P >0.05). Vechur had lesser seasonal fluctuations in major constituents, indicating it’s adaptability and climatic resilience as the native breed of Kerala.

A study was undertaken to evaluate carbohydrate and protein fractions of crop residue based complete rations as per the procedure of Cornel Net Carbohydrate and Protein (CNCPs) system.  Three iso-nitrogenous complete rations were prepared comprising of maize stover (T1) straw , red gram straw (T2) and black gram (T3) and concentrate mixture in 60: 40 ratio, respectively and were analyzed for CNCPS fractions. Maize stover contained lower (P<0.01) lignin (% NDF) compared to red gram or black gram straws. Lignin (% NDF) was lower (P<0.01) and starch (% NSC) was higher (P<0.01) in T1  when compared to T2 or T3. NDICP (% CP) was higher (P<0.01) and ADICP (% CP) was lower (P<0.01) in T1 when compared to other complete rations. Carbohydrate fraction CA (% CHO) was higher (P<0.01), while fraction CC (% CHO) was lower (P<0.01) in T1 when compared to other complete rations. Protein fractions PB1 and PB3 (% CP) were higher (P<0.01) in T1 while the fraction PC (% CP) was similar among the complete rations under study. Similar trend of higher (P<0.01) CA, PB2 and PB3 and lower (P<0.01) CC fractions were observed in maize stover than in red gram or black gram straw. The present study concluded that complete ration (T) comprising of maize stover was better in terms of carbohydrate and protein fractions with higher (CA, PB1and PB3) and lower CC and PC fractions when compared to other complete rations.

Gastrointestinal nematode parasitism is one of the major factors limiting sheep production worldwide because they cause heavy economic losses in meat and wool production. Gastrointestinal parasitism is the major cause for morbidity and mortality in ruminants. Severe anemia, reduction in functional gastric gland mass, severe damage to gastric mucosa and villous astropy caused by these worms are responsible for the death due to parasitic gastroenteritis. In India, the common nematode species encountered is Haemonchus contortus in small ruminants. This review throws light on the different mechanisms and contributory factors affecting the development of anthelmintic resistance, the diagnosis and means to prevent the resistance at field level. The emergence of multi-resistant nematode has shown that the previously used control strategies is no longer a chemically success method. The interpretation of fecal egg count reduction test has been modified and suggestions are made on its use with persistent anthelmintics. 

With the advancement of research and development of medical technology, there is an increase in the number of animals used in research. As millions of experimental animals are being used in different experiments worldwide, there is a lot of debate about the pain, distress, and death experienced by animals during scientific experiments. Experimental animals also require skilled manpower, time-consuming protocols and are costly. There are various alternatives to animal testing to overcome the drawbacks of animal experiments and avoid unethical procedures. Russell and Burch published principles of the Humane Experimental Technique which includes a strategy of 3 Rs (i.e. reduction, refinement, and replacement) in 1959. They introduced and defined the terms replacement, reduction, and refinement, which subsequently have become known as ‘alternatives’ or ‘alternative methods’ for minimizing the potential for animal pain and distress in biomedical research. Therefore, different methods and different alternative organisms are being used to implement the 3 Rs strategy. So, a brief account of these alternatives and the advantages associated is discussed in this review with examples. An integrated application of these approaches would give insight into the minimum use of animals in scientific experiments.

The socioeconomic importance of nomadic donkey rearing, perception on health benefits of donkey milk and the marketing channels involved remain unexplored. This paper aims at providing details on nomadic donkey rearing, a traditional system prevailing in Tamil Nadu. Donkey played a significant role in the livelihood of its owners who had migrated throughout Tamil Nadu for selling donkey milk.  They traversed around 30 – 40 km per day to sell the donkey milk besides meeting the grazing needs of the donkeys. Majority of the nomadic donkey rearers were young to middle aged and were scheduled tribes. Two third of the respondents were involved in nomadic donkey rearing for nearly eight months in a year and for the remaining four months they earned their livelihood as  agricultural labourers. The study revealed that on an average, lactating jenny yield milk for six months. At the end of the lactation period, the donkey rearers sold the dry jenny to the traders and in turn purchased the lactating jenny from them. The nomadic donkey rearers believed that the donkey milk had medicinal benefits to cure ailments such as ulcer, indigestion, pneumonia,  jaundice, leukorrhea and hypernatremia. The respondents preferred institutional support in marketing donkey milk so that they could settle in one place and thrive better. 

The prevalence of haemoparasites in dogs in different regions of Andhra Pradesh was presented in this study. The overall prevalence of haemoparasitic infection was 35.0 and 48.23 per cent in Rayalaseema and Coastal Andhra regions, respectively. Statistically, there was no significant (P>0.05) relationship between the region and prevalence of haemoparasites in dogs. Infection with single haemoparasite and co-infection with more than one haemoparasites was non-significantly higher (32.62% and 15.60%, respectively) in dogs of Coastal Andhra than in Rayalaseema region (27.50% and 7.50%, respectively). The prevalence of Babesia spp., Ehrlichia canis and Hepatozoon canis was non-significantly (P>0.05) high in Coastal Andhra than in Rayalaseema region. Among three species identified Babesia spp. were the most prevalent species in dogs in two regions. Co-infection with Babesia spp. and E. canis (10.06%; P>0.05) was more frequently observed in dogs in Coastal Andhra region than in dogs of Rayalaseema region (6.25 %). 

An experiment (97 days) was conducted to investigate the dietary lauric acid (LA) supplementation on performance, digestibility and faecal microflora counts in Large White Yorkshire cross piglets. A basal diet was (BD) prepared as a negative control without supplementation and a positive control with an antibiotic (chlortetracycline at 0.05%) supplementation (BDA). Another two diets were prepared by supplementing LA at 0.2 and 0.4% levels to the basal diet. Dietary inclusion of LA or antibiotic significantly (P<0.01) improved the body weight and feed efficiency and recorded highest (P<0.01) body weights with 0.4% LA, while lowest (P<0.01) weight gain with control group. Significantly higher FCR (P<0.01) was observed in LA fed animals and the lowest (P<0.01) was recorded in the BD and BDA groups. The improved (P<0.05) digestibility of organic matter, crude fiber, ether extract and nitrogen free extract was observed with 0.4% LA. The faecal total bacterial count and E.coli count were lowered (P<0.01) with LA supplementation, while highest count was observed in control group. Hence, it was concluded that, supplementation of LA at 0.2 to 0.4 % in the diets of LWY piglets showed increased weight gain, feed efficiency and nutrient digestibility by reducing faecal microflora count in LWY piglets.