A corn culture of Fusarium roseum was added to a standard corn-soybean swine gestation ration. Low, middle, and high dosage mixed feeds contained 7, 38, and 64 mg of zearalenone/kg of feed (7, 38, and 64 ppm) and 0.5, 2.5, and 4.5 mg of deoxynivalenol/kg, respectively. Control feed was the standard ration without added F roseum corn culture. Mature gilts were bred by natural service and fed control or F roseum molded feed from 3 to 34 days after breeding. The main effect of the molded feed was an inhibition of fetal development, with decreased numbers of fetuses present in treated animals at slaughter (38 to 43 days after breeding). Normal litters were present in 7 of 8 control animals, in 2 of 4 gilts given the low-dosage feed, in 1 of 4 gilts given the medium dosage, and in 0 of 4 given the high-dosage feed. Corpora lutea were maintained in all treated animals, as evidenced by serum progesterone concentrations. Serum estradiol concentrations were decreased in gilts in the middle- and high-dosage groups. The genital system of the gilts fed low- and middle-dosage feeds had a gross and microscopic appearance similar to that of the pregnant controls and reflected prolonged progesterone stimulation. Morphologic changes in the genital system of the high-dosage group were intermediate between changes induced by progesterone and those induced by estrogen. Clinical signs of hyperestrogenism and partial feed refusal were noticed in only some of the high-dosage group animals.

Cytauxzoon felis, susceptibilities of (i) domestic cats to inoculation with infected bobcat blood and ground tissues; (ii) domestic cats to subinoculation with blood from cats having received bobcat blood; (iii) inoculated cats to subsequent challenge exposure with deep-frozen virulent inoculum of domestic cat origin; and (iv) eastern bobcat to reinoculation with various doses of virulent Cytauxzoon inoculum of domestic cat origin; additional experiments to determine if piroplasm levels in bobcats and domestic cats could be raised to maximize chances for further transmission of Cytauxzoon to domestic cats

Fasciola hepatica, calves (exper.), age-related susceptibility to infection determined by fecal egg counts at various sampling times following infection, numbers of flukes in liver of calves at slaughter, and antibody response as evidenced by enzyme-linked immunosorbent assay

This study was performed to clarify the clinical signs of macroscopical lesions of pigs naturally infected with hog cholera. There was clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. In the clinical inspection of the natural cases, diarrhea (73.1%), blotching of ear (50.0), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardial hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of large intestine and splenic infarction were seen mainly

The presence of fibrinous thrombi in the blood vessels of multiple organs was observed in chickens which died within approximately 3 days post inoculation. The density of fibrinous thrombi (i.e., the number of thrombi per section) was greatest in the lung, followed by spleen, kidney, liver and heart. The cause of death of the chickens after infection with acute fowl cholera was probably due to an endotoxin (septic) shock accompanied with DIC in multiple organs

A polyvalent live Eschericia coli oral vaccine were prepared by the use of 5 field isolates of enteropathogenic E. Coli, serotypes 08: K87, K83a, b; 0138: K81, K88a, c; 0141: K85a, b, K88a, b: 0149: K91, K88a, c and 0157: K'V17' K88a, c. Some field experiments were conducted to investigate the effectiveness of the polyvalent live E. coli oral vaccine in the prevention of neandatal colibacillosis in piglets suckling orally vaccinated sows. Seventy-nine pregnant sows in and intensive pig farm were vaccinated with oral vaccine 4 weeks prior to farrowing and 19 sows were chosen for control. The piglets suckling vaccinated sows showed a significant protection against neonatal enteric colibacillosis during the 2 weeks observation period from the farrowing but no significant differences in protection between vaccinated and control group were observed with piglets older than 15 days