Industrialization and Urban sprawl together with population growth and increases in water consumption cause water pollution and destruction of natural resources quality; these are followed by reducing access to available resources such as drinking water. Every year a significant amount of urban waste water is discharged to water resources, while natural treatment is impossible. Cities in each level require different facilities and infrastructure. optimal resource utilization with appropriate site selection for water & wastewater facilities have an important role in water quality in the major cities and can control water pollution, so it has been considered to increase the quality of life in cities, also the neglect of attention to climate condition such as morphology, hydrology and topography cause negative impacts on urban environment. There are different models and methods to select suitable sites for facilities. They are specifically important in arid land where water resources have become increasingly scarce. One of the methods is zoning. In this paper satellite images have been used to locate facilities in a typical arid city in Iran, Shiraz. The large-scaled (landscape scale) land use maps has been prepared for Shiraz-Neiriz water basin, and the distinctive zones were determined base on arid and semi arid geo-hydro morphology. Then each zone were analyzed using large-scale land use, soil and topographic factors to determine adequate potential sites for facilities by regarding sustainable development and considering the cumulative effects of upstream area. At the end, some suggestions were determined to reduce urban environment pollution.