This experiment was designed to investigate the effects of antibiotic, vitamin E and rosemary essential oils in various doses on some blood parameters, beneficial and harmful microorganisms in instentine jejunum microflora of lying hens. The experiment was conducted according to random parcel experiment design. A total of 240 Bovans genotype and 32 weeks aged were equally divided into 6 groups (8 hens in each group with 5 replicates). While the control group was fed with basal diet the treatment groups were supplemented with 500 mg/kg antibiotics; 200 mg/kg vitamin E; 100, 200, and 300 mg/kg REO to basal diet for 90 consecutive days. The result showed that there were no effects of all additions to basal diets on examined blood parameters. Antibiotic and all rosemary essential oils doses to basal diet affected the instentine jejunum bacteria content by decreasing probable coliforms, faecal coliforms, Escherichia coli (E. coli) and Clostridium perfringens (Cl. perfringens) bacteria level significantly. While a 100 mg/kg rosemary essential oils dose was of the same influence with antibiotic (500 mg/kg) on all bacteria species, 200 and 300 mg/kg doses applications were more effective on E. coli compare to antibiotics. 300 mg/kg doses applications dose was more effective on probable faecal coliforms than antibiotics. As conclusion, the results shows the rosemary essential oils has the high antimicrobial effect on some pathogenic bacterias and could be used in laying hen for feed addition.

Bu çalışmada yeme antibiyotik (amoksisilin+klavulanik asit) ve probiyotik ilavesinin gökkuşağı alabalıklarında (Oncorhynchus mykiss) bazı immünolojik ve serum biyokimyasal sağlık karakteristikleri üzerine etkilerinin araştırılması amaçlanmıştır. Yeme ilave edilen antibiyotik veya probiyotik katkılarının lizozim aktivitesi, myeloperoksidaz aktivitesi, serum total protein, albümin, globülin, trigliserit ve kolesterol değerleri üzerine herhangi bir etkisinin olmadığı belirlenmiştir. Antibiyotik ile beslenen balıkların serum glikoz düzeyleri kontrole göre önemli oranda artmıştır. Bununla birlikte antibiyotik ile beslenen balıkların GOT değeri kontrole göre önemli oranda azalmıştır. Ayrıca LDH ve ALP değerleri antibiyotik ve probiyotik ilavesi ile kontrole göre azaldığı belirlenmiştir. Bu çalışma, tek bir deneysel model olup farklı balık türlerinde ve farklı balık patojenlerinde karşı probiyotik kullanımı farklı dozlara veya zamana bağlı olarak değişebilir. Bu nedenle bu çalışma çeşitli kan parametrelerinin değerlendirilmesi açısından diğer çalışmalara ışık tutmaktadır.

In this study the resistance of 200 Enterobacteriaceae isolates recovered from seawater in Giresun Coasts (Black Sea) to 9 different antibiotics was investigated by agar diffusion methods. Antibiotic resistance levels of isolates was determined respectively, Erythromycin (E): 82%, Cefazolin (CZ): 46.50%, Cefotaxime (CTX): 50.50%, Amikacin (AK): 41.50%, Nalidixic acid (NA): 34.50%, Tetracycline (TE): 30.50%, Chloramphenicol (C): 36.50%, Cefuroxime (CXM): 35.50% and Ampicillin (AM): 15.50%. It was found that 2 isolates resistant to all antibiotics, 5 isolates sensitive and 91% of all isolates multiple antibiotic resistance (MAR) index values were higher than 0.2. It was concluded that bacteriological quality in Giresun coastal area could cause public health problems due to the not provided necessary hygiene and sanitation.