The objective of this study was to determine the energy use and greenhouse gas emissions associated with sesame production. Energy use efficiency indicators and greenhouse gas emission rates were calculated for the 2022-2023 production season. The energy input and output for sesame production were found to be 12079.15 MJ ha-1 and 30052.44 MJ ha-1, respectively. The study found an energy use efficiency of 2.49, with a specific energy of 12.20 MJ kg-1, an energy productivity of 0.08 kg MJ-1, and a net energy value of 17973.29 MJ ha-1. The direct and indirect energy inputs were calculated to be 4584.41 MJ ha-1 (37.95%) and 7494.74 MJ ha-1 (62.05%), while the renewable and non-renewable energy inputs were calculated to be 469.12 MJ ha-1 (3.88%) and 11610.03 MJ ha-1 (98.65%), respectively. The calculation shows that the total greenhouse gas emissions are 380.52 kgCO2-eq ha-1 and the greenhouse gas emission rate is 0.38 kgCO2-eq ha-1. Sesame production is highly profitable for the 2022-2023 production season in terms of energy use efficiency.