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The Effect of Different Grape Varieties and Adding Different Ratios of Mustard Seeds on the Phenolic Compounds, Antioxidant Capacity, and Bioaccessibility Values of Hardaliye under In Vitro Digestion Texte intégral
2024
Ayşe Semra Aksoy | Mustafa Yaman | Muhammet Arıcı
Hardaliye, grape-based fermented beverage, rich in antioxidant phenolic compounds. Bioaccessibility and antioxidant capacity of bioactive compounds in hardaliye, produced using varying amounts of mustard seeds (1%, 1.5%, and 2%) with Merlot and Papazkarası grape varieties, were evaluated under in vitro gastrointestinal digestion conditions. After digestion, Merlot and Papazkarası samples with 2% addition of mustard seed showed significantly higher total phenolic compounds (TPC) (358.48±14.73 and 89.01±2.42 mg GAE/L, respectively) compared to other samples (P<0.05). 2% mustard seed added Merlot samples resulted in the highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) and cupric reducing antioxidant capacity (CUPRAC) values (19.06±3.91 and 9.96±1.83 mmol TEAC/L, respectively) which differed significantly from other samples (P<0.05). The Merlot sample with 2% addition of mustard seed showed significantly higher TPC, total flavonoid compounds (TFC), DPPH, and CUPRAC bioaccessibility values compared to other Merlot samples (P<0.05). For Papazkarası samples with 2% mustard seed addition, significant differences were observed only in terms of TPC and TFC bioaccessibility values (15.87±2.30% and 15.27±1.29%, respectively) compared to samples with 1% and 1.5% mustard seed addition (P<0.05). The study demonstrated that the bioaccessibility of bioactive compounds in hardaliye can vary depending on the grape variety and to some extent, the use of mustard seed. This suggests that the food matrix and interaction with other food matrices in the environment can affect the stability and bioavailability of bioactive compounds during simulated digestion.
Afficher plus [+] Moins [-]Çimento Yerine Sığır Gübresi Külünün Kısmi İkamesi ile Üretilen Hafif Betonun Bazı Özelliklerinin Belirlenmesi Texte intégral
2024
Ahmet Korkmaz | Sırrı Şahin
Çimento Yerine Sığır Gübresi Külünün Kısmi İkamesi ile Üretilen Hafif Betonun Bazı Özelliklerinin Belirlenmesi Texte intégral
2024
Ahmet Korkmaz | Sırrı Şahin
Bu çalışmada; Türkiye'de kırsal alanlarda ısınma amaçlı olarak kullanılan yenilenebilir enerji kaynaklarından güneşte kurutulmuş sığır gübresi külünün (SGK) farklı oranlarda çimento yerine kullanılmasının, hafif betonun basınç dayanımı üzerine etkisinin araştırılması amaçlanmıştır. Araştırmada, hafif agrega olarak pomza bağlayıcı olarak da CEM I 42,5 R tipi çimento ve SGK ikamesi kullanılmıştır. Karışımlara çimento yerine ağırlıkça belirli oranlarda (%0, %5, %10, %15 ve %20) SGK ikame edilerek 5 grup halinde toplam 45 adet 150×150×150 mm’lik küp numune üretilmiştir. Taze beton deneyleri olarak-birim ağırlık deneyleri; serleşmiş beton deneyleri olarak da kuru birim ağırlık, su emme ve basınç dayanımı deneyleri yapılmıştır. SGK kullanılan numunelerde, SGK ikamesinin artması ile kontrol örneklerine göre su emme miktarında bir miktar artış, basınç dayanımlarında ise bir miktar düşüş görülmüştür. %5, %10, %15 ve %20 oranlarında SGK ikamesi ile üretilen numunelerin 28 günlük basınç dayanımı düşüş değerleri kontrol örnekleri ile karşılaştırıldığında sırasıyla %4, %4,6, %5,5 ve %6 olarak belirlenmiştir. Çimento yerine %20 SGK ikamesinin uygulanması, numunelerin 28 günlük basınç dayanımlarında %6’lık bir azalma gözlemlenmiştir.
Afficher plus [+] Moins [-]Evaluación de familias de zapallo (Cucurbita moschata Duch.) seleccionadas por mayor contenido de materia seca en el fruto y otras características agronómicas Texte intégral
2010
Tobar Tosse, Dora Enith(Universidad Nacional de Colombia Sede Palmira Facultad de Ciencias Agropecuarias) | Vallejo Cabrera, Franco Alirio(Universidad Nacional de Colombia Sede Palmira Facultad de Ciencias Agropecuarias) | Baena García, Diosdado(Universidad Nacional de Colombia Sede Palmira Facultad de Ciencias Agropecuarias)
Se evaluaron cuatro familias de hermanos completos de zapallo, Cucurbita moschata Duch, provenientes de dos ciclos de estabilización genética mediante cruzamientos fraternales y seleccionadas por mayor contenido de materia seca (MS) en el fruto y buenas características para consumo en fresco. La familia F7a sobresalió por su mayor contenido de materia MS en el fruto (15.86% ± 2.17) en comparación con el testigo comercial Unapal-Bolo Verde (10.68% ± 2.08), forma esférica levemente achatada, color externo amarillo claro, color de pulpa amarilla a salmón, espesor de pulpa de 3.71 ± 0.58 cm y peso promedio del fruto de 3.10 ± 0.73 kg, que la convierte en una alternativa para consumo en fresco. | Four full-sib families of squash, Cucurbita moschata Duch, from two cycles of genetic stability through crosses fraternal and selected by a higher content of dry matter in fruit and good characteristics for fresh consumption was evaluated. The F7a family had at increased dry matter content in fruit (15.86% ± 2.17) compared with the control-commercial Unapal Bolo Verde (10.68% ± 2.08), slightly flattened spherical form, external color yellow, light yellow flesh color to salmon, flesh thickness of 3.71 cm ± 0.58 and average fruit weight of 3.10 kg ± 0.73, which makes it an alternative for fresh consumption.
Afficher plus [+] Moins [-]INJURY OF WHEAT LEAF MINER LARVAE Syringopais temperatella Led. ON TWO WHEAT VARIETIES UM -RABEE & TELL-AFAR Texte intégral
2012
S. Adullah | Mohammed Ghani
A field experiment was conducted out of college of agriculture and forestry during the growing season of 2007- 2008. The aim of the present study is to determine the damage of the larvae of wheat leaf miner larvae Syringopais temperatella Led., for two wheat varieties Um-RAbee & Tell-Afar3.. The result of this research revealed that the percentage of infested plants and leaves were positively proportional with increasing the number of larvae and negatively to the crops components. The injury was more obvious with the bread wheat variety (Tell-Afar 3) in which it was observed that the larvae favorites this variety more than the other one especially when added 100 larva / m2 at 12 / 4 / 2008 in percentage of infested plants & leaves reached 96.66 and 90.79 % respectively. Moreover, Tell-Afar3 variety gave the lowest values in the characteristics (leave area, weight of flag leave, weight of biological yield, number of spikes, length of spike, number of grains in spike, weight of 1000 grains, and grain yield ) with an averages of (9.07 cm 2, 0.046 mg, 425.00 g/m2, 200.00 spike / m2, 2.65 cm, 7.56 grain / spike, 33.18 g and 144.00 g/m2), for each, respectively. Whereas the durum wheat variety Um-RAbee was less favorite from larvae in which it was reflected in the percentage of number of infested plants and leaves plants and yield components in which the lowest percentage of infested plants and leaves were 83.33 and 67.89 % ,respectively. As well as it was showed increase in the characteristics (leave area, weight of flag leave, weight of biological yield, number of spikes, number of grains in spike, weight of 1000 grains, and grain yield ) with an average mean of (10.87 cm 2, 0.057 mg, 480.00 g/m2, 216.33 spike /m2, 9.30 grain / spike, 38.55 g and 167.63 g/m2) for each, respectively.
Afficher plus [+] Moins [-]Colic in horses: Effects of dietary factors Texte intégral
2024
Şevket Evci
Studies on colic, an economically important metabolic disease in horses, have typically emphasized maintenance characteristics. However, recent research has demonstrated that nutrient content also contributes to the development of colic. Microbial fermentation of the diet begins in the stomach and continues through the hindgut. During this process, various substrates are produced, including acetate, propionate, butyrate, and methane. The gut contains bacteria such as Firmicutes and Bacteroidetes, but the dominance of one over the other is influenced by the type of substrate available in the gut, such as oat, barley, wheat, corn, etc. Microbial fermentation in the equine cecum is markedly influenced by the pH balance of the nutrient metabolism. This has varying impacts on the cecal microbiota. Investigations into the effects of different feeding methods and nutrients have yielded diverse outcomes for the etiology of colic and post-colic nutrition. The objective of this review is to assess the impact of nutrition and diet composition on the etiology of colic in horses, investigate the role of additives in preventing colic cases, and analyze the results of several studies.
Afficher plus [+] Moins [-]Effects of Ultrasound Application on the Improvement of Probiotic Properties and Antioxidant Activity of Kluyveromyces marxianus, Saccharomyces cerevisiae var. boulardii and Saccharomyces cerevisiae Texte intégral
2024
Hamza Goktas | Demet Turali | Cansu Agan | Osman Sagdic
Effects of Ultrasound Application on the Improvement of Probiotic Properties and Antioxidant Activity of Kluyveromyces marxianus, Saccharomyces cerevisiae var. boulardii and Saccharomyces cerevisiae Texte intégral
2024
Hamza Goktas | Demet Turali | Cansu Agan | Osman Sagdic
The objective of this study was to ascertain the impact of ultrasound application on the probiotic characteristics and antioxidant activity of yeasts. In this context, the pH changes, probiotic properties and antioxidant activities of K. marxianus (Km), S. boulardii (Sb) and S. cerevisiae (Sc) were determined by ultrasound application at different durations (5, 15, 30 and 60 minutes at 24 kHz). The lowest pH values were determined for cultures of Km (ultrasound non-applied K. marxianus), Sb-30 (30 min. ultrasound applied S. boulardii) and Sc-5 (5 min. ultrasound applied S. cerevisiae) as 4.48, 5.15 and 5.26, respectively. The hydrophobicity values of the yeast strains varied between 6% and 24%, increased with ultrasound application. Although S. boulardii had the highest tolerance to low pH and bile salts, the resistance of all yeast to low pH and bile salts decreased with ultrasound application. K. marxianus had the least survival under in vitro conditions, but ultrasound application increased survival of K. marxianus strains and slightly affected the survival rate of S. boulardii and S. cerevisiae. Increasing of duration time of ultrasound application resulted higher antioxidant activity and so the highest antioxidant activity was determined for Sb-60. Finally, ultrasound application could be used for the development of hydrophobicity and antioxidant properties of yeast cultures.
Afficher plus [+] Moins [-]Efecto del derivado de la lactosa sobre la población microbiana de muestras fecales de cerdos posdestete Texte intégral
2006
Rosero, Olga Lucía
COMPENDIO Se estudió el efecto prebiótico del derivado de la lactosa (DL) en la población microbiana presente en las muestras de heces (inóculo fecal) de los cerdos posdestete. Se utilizó la técnica de producción de gas in vitro en 2 sustratos: el control pulpa de remolacha (PR) y DL. Se desarrollaron dos etapas. En la primera se determinó la producción del gas y las proporciones de ácidos grasos volátiles (AGV), evaluando la actividad microbiana en los niveles (0, 0.2, 2, 20 y 100%) de DL reemplazando a la PR, durante la fermentación de 144h. El tiempo medio de la producción del gas potencial se alcanzó a las 12h de la fermentación. Este tiempo se utilizó para la segunda etapa con tres niveles de DL (0, 20 y 100%). Se determinó el efecto del DL sobre la composición de la población microbiana (E. coli, lactobacillus y anaerobios facultativos totales), concentración de AGV y sobre el pH, como resultado de la fermentación bacteriana . Se incrementó la concentración del butirato (P < 0.001) y la acidificación (P < 0.001) del medio. El DL modificó la composición microbiana, que se reflejó en la disminución (P < 0.001) del número de colonias microbianas de E. coli. En conclusión el DL en niveles altos presentó efectos prebióticos. Palabras claves: Lactosa, prebiótico, fermentación in vitro, cerdo, butirato, Escherichia coli ABSTRACT Effect of Lactose Derivative (LD) on the present microbial populationʼs in the sample faeces of weaned piglets The prebiotic effect of Lactose Derivative (LD) on the present microbial populationʼs in the sample faeces (faecal inocula) of weaned piglets was studied . The in vitro gas-production technique was used. Using 2 substrates: sugarbeet pulp (SBP) as control and LD as evaluation. Two stages were developed. In the first it the gas production and the Volatile Fatty Acids (VFA) proportions, during 144h fermentation, to evaluate the effect of the microbial activity with different DL levels (0, 0.2, 2, 20 y 100%), as replacement to SBP was determined. The half time gas production potential, was reached at the 12h of fermentation. This time was used for the second stage and the DL levels (0, 20 and 100%). Microbial populationʼs composition (E. coli, Lactobacillus and total facultative Anaerobes), VFA concentration and pH was determined. Effects of the DL were presented on the products of the bacterial fermentation in faecal inocula. An increment in the butyrate concentration (P
Afficher plus [+] Moins [-]Determination of Antifungal Activities on Some Plant Extracts on Alternaria alternata Texte intégral
2024
Derya Öğüt Yavuz | Havva Dinler | Ayşe Uysal Morca
Determination of Antifungal Activities on Some Plant Extracts on Alternaria alternata Texte intégral
2024
Derya Öğüt Yavuz | Havva Dinler | Ayşe Uysal Morca
To increase yield and quality in agricultural production, it is necessary to perform management against diseases and pests. Alternaria, which causes several diseases in many economically important plants, is the most common species and widely distributed in nature. One of the important species reported in sweet cherry in recent years is Alternaria alternata. Many studies have emphasized the necessity of effective control with Alternaria species and examined the use of environmentally friendly methods against fungal diseases. In recent years, the use of plant extracts has increased due to their antimicrobial properties. Antifungal effects of Datura stramonium L., Vitex agnus-castus L., Xanthium strumarium L., Capsella bursa-pastoris L., Convolvulus arvensis L., Viscum album L., Echinophora tenuifolia L. subsp. sibthorpiana (Guss.) Tutin, Amaranthus retroflexus L., Chenopodium album L., Tribulus terrestris L., Solanum nigrum L., Nerium oleander L., Circium arvense (L.) Scop. and Brassica oleracea L. aqueous extracts were determined against Alternaria alternata. At the end of the 7-day incubation period, the mycelial growth of the fungi was measured and the antifungal effect of plant extracts was determined. As a result, the extracts were determined to inhibit mycelial growth compared to control. The plant water extracts used in the study were determined to inhibit the mycelial development of the pathogen by 20.20% to 77.12%. It is considered that different solvents and concentrations should be addressed to guide further studies. It was also concluded that potential plant species that may show anti-fungal properties should be evaluated.
Afficher plus [+] Moins [-]Evaluation of tolerance to Phytophthora cinnamomi Rands in avocado (Persea americana Miller.) germplasm Texte intégral
2017
Rodriguez Henao, Eberto | Caicedo Arana, Álvaro | Enriquez Valencia, Ayda Lilia | Muñoz Florez, Jaime Eduardo
In order to obtain twenty-one evaluated accessions from the Avocado Germplasm Bank of CORPOICA, Palmira Research Station with two pathogenic strains of the oomycete, Phytophthora cinnamomi Rands. The aim of this research was to identify avocado accessions, which used as rootstocks in a cultural control strategy for preventing root rot disease. Disease progression was evaluated using mycelium of the pathogen by cut-stem inoculation. The measurements of symptom progression length and width were carried out and analyzed. In order to obtain the area under the disease progression curve (AUDPC), these data were analyzed. A randomized complete block design (RCBD), with a factorial design of 3 x 21 in-subdivided parcels (2 strains of the pathogen, a control strain, and 21 avocado accessions) was performed. Eight readings were determined per plant throughout evaluation time. Statistical analysis showed significantly differences using the AUDPC for some avocado accessions. Tukey's test revealed five tolerance levels. Accession ‘NATU-001’ from Tumaco, Nariño, was identified as promising for its high tolerance and ‘CANO-008’ from Norcasia, Caldas, as a tolerant control accession had the second lowest value of AUDPC. Susceptible accessions used as control, e.g. ‘Hass’ variety and rootstock ‘Topa-Topa’, performed a very high susceptibility to the pathogen along with ‘QUIQUI-030’ accession from Quimbaya, Quindío, Colombia
Afficher plus [+] Moins [-]Monitoring Trends in Packaged Food Supply for Added Sugar and Sweeteners: Are We Jumping out of the Frying Pan into the Fire? Texte intégral
2024
Murat Gürbüz | Selinay Demirel | Miray Nur Aykut | Esma Nur Erdoğan | Beyza Balcı | Gözde Özaslan
Excessive sugar intake can lead to poor health outcomes. The use of sweeteners is considered as a strategy to reduce added sugar consumption. The presence of sweeteners in food products has increased significantly in many countries. Therefore, the aim of this study was to identify the added sugars and sweeteners in packaged products. 1550 (57.9%) out of 2676 food products contained at least one added sugar. Confectionery and desserts (35.38±24.82 g/100 g), and snack foods (20.70±16.20 g/100 g) were the main categories containing the highest amount of added sugar. 229 (8.6%) out of 2676 food products contained various types of sweeteners. The most popular added sugar was sucrose (62.9%), while the most popular sweetener was sorbitol (28.2%). This is the most comprehensive study in the city center of Edirne province in Türkiye reporting on the types and frequency of added sugars and sweeteners in packaged products. This study offers monitoring to improve the legislation of Türkiye on added sugars and sweeteners used in the food supply.
Afficher plus [+] Moins [-]Effects of Partially Replacing the Commercial Soybean Meal, With A Soaked and Boiled Raw Full-Fat Soybean in Broiler Diets Texte intégral
2024
Mammo Mengesha Erdaw | Alemayehu Guteta
The aim of this study was to investigate the effects of partially replacing the commercial soybean meal (SBM) with a home-treated, locally produced raw-full fat soybean (RFFSB) in the diets of broilers. A 3×2×2+1 factorial arrangement was used to conduct this feeding trial. A test ingredient (RFFSB) was differently soaked (0, 6 or 12 hrs), drained, boiled (25 or 35 min) and sundried. Following this, it was hammered to pass through a 0.2-mm sieve, then 12 experimental diets were formulated, replacing the SBM by such a home-treated-RFFSB at 50 or 75%. The control diet didn’t contain any RFFSBN. Totally 13 experimental diets were prepared and every treatment was replicated 3 times and 10 chicks per replicate. The results revealed that replacing the commercial SBM by a treated RFFSB had no significant interaction effects on any measured parameter. However, soaking and then boiling it (RFFSB) had significant (P<0.05) interaction effect on the BWTG (1-13d and 14-28d). When increasing the soaking time, the FI (feed intake), BWTG (body weight gain) and feed efficiency were significantly (P<0.05) decreased. When increasing the boiling duration, both FI and feed efficiency (14-28d) were improved. But, when increasing the replacement rate of RFFSB, the feed efficiency was deteriorated. Broilers fed on both control and diets, containing a non-soaked RFFSB had higher (P<0.05) BWTG (1-13d). Birds fed on diets containing RFFSB that was soaked for the longest period (12 hrs) had significantly lower BWTG. Birds fed on diets, containing prolonged boiling duration had significantly (P<0.05) higher BWTG and feed efficiency. There was no interaction (P> 0.05) effect on both carcass yield and cut-products. Neither increasing a boiling time nor a replacement rate had (P<0.05) any influence on the WT (weight) of the carcass. Birds on both control and on non-soaked RFFSB diets had better WT of carcass products. There was no interaction (P>0.05) effect on organ developments. However, increasing the soaking-duration significantly (P<0.05) reduced the organ developments. Therefore, it is concluded that commercial SBM can be replaced by a non-soaked, but boiled raw soybean in diets of broilers.
Afficher plus [+] Moins [-]Kırmızı ve Beyaz LED Işığın Zenginleştirilmiş Kafeslerde Yetiştirilen Yumurta Tavuklarının Performansı, Yumurta Kalitesi ve Bazı Davranış Özellikleri Üzerine Etkisi Texte intégral
2024
Nazlı Tez | Mustafa Akşit
Bu çalışmanın amacı, kırmızı ve beyaz LED ışığın yumurtacı tavukların eşeysel olgunluğu, performansı, yumurta kalitesi ve bazı davranış özellikleri üzerindeki etkisini belirlemektir. On altı haftalık toplam 432 kahverengi yumurtacı yarka (Lohmann) rastgele her biri 12 tekerrürlü 2 uygulama grubuna ayrılmıştır. Uygulama grupları 1) Monokromatik kırmızı LED aydınlatma ve 2) Beyaz LED aydınlatma gruplarından oluşturulmuştur. Kanatlılar, deneme süresince (16-32 hafta) zenginleştirilmiş kafeslerde barındırılmıştır. Tavukların monokromatik kırmızı ışıkta beyaz ışığa göre eşeysel olgunluğa 5 gün ve pik yumurta verimine 4 gün daha erken ulaştıkları ve deneme boyunca % 2,05 daha fazla yumurta ürettikleri belirlenmiştir. Aynı dönemde ışık renginin yem tüketimine ve yemden yararlanma oranına (YYO) etkisi önemli bulunmamıştır. Ancak, yumurta veriminin yüksek olduğu 21, 23-26 ve 29. haftalarda tavukların kırmızı ışıkta daha iyi YYO değerlerine sahip oldukları görülmüştür. Yumurta ağırlığı ve yumurta kitlesi kırmızı ışıkta daha yüksek bulunmuştur. Işık rengi, tavukların yumurta kalite özellikleri, tünek ve folluk kullanımı ve kırık yumurta oranı üzerinde önemli bir etkide bulunmamıştır. Sonuç olarak, büyüme döneminin sonunda başlayan monokromatik kırmızı LED ışık uygulaması kanatlıların daha erken eşeysel olgunluğa ulaşmalarını ve yumurtlama döneminde daha fazla yumurta üretmelerini sağlamıştır.
Afficher plus [+] Moins [-]Evaluation of Fruit Juices as Probiotic Delivery Systems: Challenges, Current Strategies and Health Benefits Texte intégral
2024
Dilara Yalmancı | Hilal Dikmen Meral | Sevda Dere | Selma Kayacan Çakmakoğlu | Osman Sağdıç | Enes Dertli
There is an increasing trend for development of alternatives to deliver probiotics with non-dairy products. Fruit juices have become one of main food products for delivery of probiotics. The availability of different fruit juice types, their fresh and healthy perception from the consumer's side and demand for plant-based products increase attention to fortification of fruit juices with probiotics. Yet, development of probiotic fruit juices is still an emerging area for the functional food concept. Probiotic juices can be developed by using both probiotic Lactobacillus and Bifidobacterium and their viability can be strain specific as well dependent on the utilized fruits. The transformation of the fruit components can play roles for the improvement of the potential health promoting functions of fruit juices which should be well-characterized. The insufficient viability of probiotic strains during shelf-life of fruit juices is one of the main challenges and efficient and relatively cheap encapsulation techniques should be developed to ensure their viability. In this study, recent achievements and developments to produce probiotic fruit juices have been summarized. Also, potential role of probiotic fortification for the health promoting functions of fruit juices related to probiotic metabolism has been discussed. Finally, strategies to increase the viability of distinct probiotics have been discussed.
Afficher plus [+] Moins [-]Neuroprotective Efficacy of β-caryophyllene on Cerebellar Changes Caused by Bisphenol A in Rats via Alleviating Oxidative Stress Texte intégral
2024
Ahmad Yahyazadeh | Fatih Mehmet Gür | Hatice Yaren Kuloğlu
Exposure to bisphenol A (BP), an environmental pollutant, is potentially harmful to both human health and the environment. The purpose of the current research was to evaluate the effectiveness of β-caryophyllene (CF) (200 mg/kg) on rat cerebellar tissues exposed to BP (250 mg/kg). Thirty-five randomly selected male rats were split into five groups as: control (CON), olive oil (OL), BP, CF, and CF+BP. On day 15 of the experiment, all rats' cerebellar tissues were immediately extracted, followed by stereological and histological examination. Our results revealed that MDA level was significantly elevated in the BP group compared to the CON group (p<0.05). While no significant difference was detected in the mean cerebellar volume among the experimental groups, the BP group’s the Purkinje cell number was significantly reduced when compared to the CON group (p<0.05). In the CF+BP group, we found a significantly lower level of MDA and higher number of Purkinje cells compared to the BP group (p<0.05). Histopathological examination revealed that the BP group had the marked neuronal deterioration; however, in the CF+BP group, this structural alteration was not as severe than the BP group. Our findings showed that exposure to BP caused oxidative damage to cerebellar tissues, and administration of CF attenuated BP-induced toxicity via improvement of oxidative stress.
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