Safe meat production is an important aspect to avoid human health hazards. The use of probiotics in poultry is an important tool to produce safe meat among several established biotechnological approaches. In this experiment, we studied the effects of probiotics for producing safe Japanese quail meat. 150 Japanese quail chicks were reared for a period of six weeks using various doses of probiotics (0, 0.5, 1, 1.5, and 2g per litre of water). The chicks were randomly distributed into five treatment groups with three replications each. The number of birds in each replication was 10. After rearing six weeks, significantly high body weight was found at probiotic concentrations of 1, 1.5, and 2g per litre of water. The feed intake in various treatments did not differ significantly, but comparatively better feed conversion ratios were observed at probiotic treatments. Water quality was not significantly differed as a result of addition of probiotics to the water. The reason for this better growth performance is probably due to the multiple benefits of probiotics in poultry. Probiotics could have maintained gut health with better nutrient utilization and availability that might have been led to higher body weight gain in the quail. In future experiments, challenging the birds with diseases or comparing probiotics with antibiotic growth promoters is required to ensure the efficiency of probiotics.

The poultry red mite, Dermanyssus gallinae (De Geer, 1778), is widely regarded as the significant ectoparasite of egg-laying hens worldwide. Since many molecular studies on poultry red mites have focused on analyzing COI and ITS1-2 genes, the present study aimed to identify 16S rDNA and the relatively understudied nuclear 18S rDNA genes of Turkish D. gallinae populations. Twenty-eight different D. gallinae populations were collected from henhouses throughout Türkiye, and the target genes were amplified using conventional PCR after morphological analysis. Haplotype analyses of the 16S rDNA sequences revealed 14 different haplotypes, with Turkish D. gallinae grouped into two of these haplotypes. The intra-species genetic variation of the 18S rDNA and 16S rDNA sequences examined in the present study and the available sequences in public GeneBank were determined as 0.17% and 0.53%, respectively. The obtained sequences belonging to D. gallinae from Türkiye were submitted to GenBank for the first time. Given the importance of identifying genetic diversity within and between species across different geographical regions, the obtained data may contribute substantially to the genetic knowledge of the PRMs.

Recent studies have shown the positive effects of Cucurbita pepo L. (pumpkin) seed oil (PSO) in different disease models. However, the effect of PSO on neurological diseases has not been clarified yet. Therefore, this study aims to elucidate the effects of BBS on pentylenetetrazole (PTZ)-induced neuronal damage and the possible roles of oxidative and nitrosative stress in this effect in vitro. The HT-22 hippocampal neuronal cell line was used in the study. Cell survival after PTZ-induced neuronal damage was evaluated with the XTT test in the groups. While the effects of BBS on total antioxidant status (TAS) and total oxidant status (TOS) after PTZ were measured with colorimetric commercial kits, its effects on neuronal nitric oxide synthase (nNOS) and nitric oxide (NO) levels were also determined by ELISA kits. In light of the data obtained, it was found that pre-treatment with PSO prevented the decrease in cell survival after exposure to PTZ. In addition, it has been found that PSO normalizes the increase in TOS, nNOS, and NO in neuronal cells after PTZ. As a result, it was determined that the treatment of neuronal cells with PSO prevented neuronal damage caused by PTZ and showed neuroprotective properties. It is thought that PSO may achieve these effects through oxidative and nitrosative systems. Enrichment of a daily diet with PSO might be beneficial in reducing the risks of neurological diseases.

Traditional milk desserts are one of the most essential dessert groups that Turkish society consumes. Due to foaming activity, it was aimed to investigate the feasibility of the ohmic heating system to produce a semolina dessert with milk. Hence, an ohmic heating treatment was used to heat the milk, semolina, and sugar mix from 20°C to 100°C using three different voltage gradients (15, 17.5, and 20 V/cm) and then boil for two minutes. It was found that the current value escalated from 20°C to approximately 86°C but decreased after 86°C due to foaming. Since the total consumed energy during the ohmic cooking treatment was inversely proportional to the treatment time, the total consumed energy values decreased based on the rising voltage gradient. As a result, the feasibility of the ohmic heating treatment for making a traditional semolina dessert with milk was determined in this study.

Diabetes is an alarming global systemic metabolic disorder that can pose a major threat to patients. The serious consequences of cigarette smoking on the diabetic kidney are not well known among people in different countries. According to different studies, smoking enhances albuminuria in diabetic patients. On the other hand, urinary albumin is a sensitive indicator of glomerular injury. The abnormal trans-glomerular passage of albumin may be seen due to increased permeability of the glomerular capillary wall and their subsequent impaired reabsorption by the epithelial cells of the proximal tubule. Smoking with hyperglycemia increases lipid accumulation and oxidative stress, which mainly up-regulates TGF-β, accumulates AGEs, reduces nitric oxide production, and eventually causes glomerular basement membrane thickening and mesangial expansion that results in the development of glomerulosclerosis and nephropathy. The complex interaction between cigarette smoking and diabetic mellitus poses multiple challenges for researchers, physicians, and patients. Therefore, the present review article aims to find out the feasible consequences for the kidney of a diabetic patient due to the habit of cigarette smoking which may be useful for academicians and researchers in the future.

Quercetin (QU) is a flavonoid found in different fruits and vegetables. Studies report that QU may have positive effects on neurological diseases. However, the effect of QU on 4-aminopyridine (4-AP)-induced neurodegeneration in neuronal cells is still not fully elucidated. In this study, the effects of QU on 4-AP-induced hippocampal neuron damage in vitro and the possible role of oxidative stress and endoplasmic reticulum stress in this effect were investigated. The study was carried out using the HT-22 hippocampal neuronal cell line. The effect of pre-treatment with QU on cell viability after 4-AP-induced neuronal damage was determined by the XTT test. Cells were evaluated histopathologically for apoptotic nuclear change (ANC) using DAPI staining. The effects of QU on oxidative stress (total oxidant state (TOS) and total antioxidant status (TAS)) occurring after neuronal damage were evaluated with colorimetric commercial kits and endoplasmic reticulum stress markers (activating transcription factor 4 (ATF-4) and C/EBP homologous protein). (CHOP) was measured with the ELISA kits. While the cell viability rate decreased in the cells treated with 4-AP, it was determined that pre-treatment with QU reversed this situation. In terms of histopathology, treatment with 4-AP increased the number of ANC, while QU pre-treatment reduced it. In addition, in terms of biochemical evaluations, TOS, ATF-4, and CHOP increased in neuronal cells after 4-AP, and QU was determined to suppress this increase. In addition, QU normalized the decreased TAS levels following the 4-AP application. As a result, in the HT-22 cell line, it was found that QU treatment had a neuroprotective effect by suppressing oxidative stress and endoplasmic reticulum stress in 4-AP-induced neuronal damage.

In the current study, the essential oil of Thymus citriodorus (Pers.) Schreb (Lamiaceae) was evaluated for its ability to control adults of two significant pests of stored products, Sitophilus granarius (Linnaeus, 1758) (Coleoptera: Dryophthoridae) and Tribolium castaneum (Herbst, 1797) (Coleoptera: Tenebrionidae), under laboratory conditions. Using a microapplicator, test insects were exposed to 0.025, 0.05, 0.1 and 0.15 µl/insect concentrations of plant essential oil in order to assess contact toxicity. At 24, 48, 72, and 96 hours following applications, deaths were noted. The experiment revealed that, depending on the insects and dosages, the essential oil showed varying degrees of contact activity. The essential oil of T. citriodorus generally had low effect on adult T. castaneum, with the greatest effect was 15.32% at 0.15 µl/insect dose after 96 hours. Adults of S. granarius showed greater sensitivity to the essential oil of T. citriodorus. After 48 hours, doses of 0.1 and 0.15 µl/insect concentrations of the essential oil resulted in over 95% of S. granarius adult mortality. The findings of the study indicate that T. citriodorus essential oil has the potential to be used in the control of S. granarius.

Agroforestry is a conventional method of land use that could help to address agricultural environmental issues. In order to take advantage of the ensuing ecological and economic interactions, agroforestry is the technique of consciously integrating woody vegetation (trees or shrubs) with crop and/or animal systems. According to recent studies, the global agri-food industry may reach more sustainable methods of producing food and fiber by adopting agroforestry techniques and principles more widely. This would benefit farmers economically and would benefit society as a whole in terms of the environment. Agroforestry promotes eco-intensification based on resource efficiency and offers a wide range of provisioning, regulating, cultural, supporting ecosystem services, and environmental advantages. In this review, we discussed agroforestry with its advantages and developments.

This study aims to define the concept of office spaces and their requirements, as well as the contemporary interior design approaches. It will also cover the interior design and application process for an architecture office in Konya. The company, originally named Çınar Architecture and active in Konya between 1985 and 1990, has been operating as Kerimler Planning Construction Consultancy Company in Konya since 1995. The company requested an interior architecture project for their new location. In the current environment, the office is starting to become outdated and is unable to offer users enough physical amenities. The main goal of the new office’s interior design was to create areas where employers and employees could collaborate in a welcoming and adaptable setting without facing any kind of discrimination. In Konya Meram Pirebi District, the Menekşe Apartment’s ground floor, which is currently a street-level store, is the site of the project, which occupies a total of 280 m2 and consists of a ground + basement. The office occupies 145 square meters on the ground floor of a recently constructed building, with glass extending to the open floor on the south, north, and west facades. The room has a very large opening because the columns are concealed by the walls, making the two stories easily visible from the entrance. The office, which occupies a 135 m2 basement floor, is connected to the elevator and staircase at the back. Natural light enters the basement through the gallery area that is attached to the staircase. Within the parameters of the study, two- and three-dimensional architectural design tools, including phases of the interior design process, were employed in conjunction with a qualitative research method based on inspection and observation. The architectural office put it into practice about half a year after the design stage. The outcome was the creation of a dynamic, modern office analysis that values teamwork and permits the emergence of unique and creative ideas throughout the project.

The farm is an abstract category in Economic theory for describing agents managing farming activity, while the real governing structures are farms of different juridical types – physical persons, sole traders, cooperatives, ago=companies, etc. Most of the time, farm’s competitiveness is inadequately assessed through technical and accountancy efficiency, factors’ productivity, profitability, market shares, etc. because critical governance aspects are ignored. This article incorporates the interdisciplinary New Institutional Economics assumptions and principles and tries to give new insights on the real competitiveness of economic organizations in modern agriculture.  It suggests a holistic framework for assessing farm’ competitiveness taking into account economic, financial, and governance efficiency, and evaluates absolute and comparative competitiveness of governing structures of Bulgarian farming. The novel assessment system includes four pillars, four criteria, 17 particular, and 5 integral indicators. The first-in-kind evaluation, based on survey data, found that the competitiveness of Bulgarian farms is good. The competitiveness of cooperatives is highest, followed by corporations and associations, sole traders, and physical persons. Critical for competitive positions of farms are: low productivity, income, financial security, and adaptability to natural environment, where public support and farms’ management strategies should be directed. Large shares of the country’s farms have low competitiveness, and if measures are not taken to improve management, restructuring, state support, etc., many farms will cease to exist in the near future. In some cases, other characteristics of governing structures like size, specialization, market orientation, and ecological location, are critical for determining competitiveness level. The suggested and successfully tested framework for assessing the competitiveness of farms should be further improved and applied more widely and periodically in the country and internationally. The precision and representativeness of the information used should also be improved by increasing the number of surveyed farms and their important characteristics. The later requires close cooperation with producer organizations, national agricultural advisory service, and other interested parties as well as extending and improving the system for collecting agro-statistical information in the country and the EU.