For the sustainable communities, there is a strong need to address the United Nations' sustainable development goals for communities, cities and countries. In this paper, we develop a unique hybrid energy system for cleaner productions of energy, fuel, food and water for an indigenous community by addressing the following goals, namely: zero hunger; clean water; affordable and clean energy; industry, innovation and infrastructure; sustainable cities and communities; and climate action. Also, the present sustainable system is investigated thermodynamically by considering energy and exergy criteria and evaluated through energy and exergy efficiencies. As a case study, the Saugeen First Nation indigenous community in the Bruce Peninsula in Ontario, Canada, is selected for meeting the demands of useful commodities where an integration of a newly developed multigenerational system with an existing nuclear reactor is achieved in order to provide food security, supply the freshwater for drinking purposes, and meet the community's electricity and heat demands. Moreover, to exploit the existing thermophysical properties of fluids in the nuclear system, a hydrogen generation unit is proposed. The novel integration is enhanced the current nuclear system and increased the variety of useful outputs. The overall system is analyzed according to the first and second laws of thermodynamics. A transient (time-dependent) analysis is carried out via hourly simulations with software packages and hourly sensitive meteorological data. The overall system performance results are obtained as 65.8% for energy efficiency and 40.1% exergy efficiency at average ambient conditions for a 126.04 mol/s hydrogen production rate.