Environmental mutagenesis, soil studies
1990
Syllanco, C.Y.L. | Inofinada, V.F. | Botuyan, M.V. | Casareno, R. (Philippines Univ., Diliman, Quezon City (Philippines). Coll. of Science)
Organic extracts of street soil samples from industrial, commercial and residential areas in Cainta, Makati, Mandaluyong, Manila, Marikina, Paranaque, Pasig, Quezon City, San Juan, and Valenzuela [Philippines] were subjected to genotoxicity studies. None of the samples exhibited direct DNA damaging potential as measured by the Rec Assay, indicating that the organic extracts of the street soil samples were not genotoxic before metabolic activation. After metabolic activation, organic extracts of street soil samples from industrial areas of Cainta, Mandaluyong, Manila, and Quezon City showed appreciable genotoxicity. The same observation was made of organic extracts from street soil samples from commercial areas of Cainta, Mandaluyong, Manila, Pasig, Quezon City, and San Juan. Appreciable genotoxicity was also observed of organic extracts from street soils of residential areas in Makati, Marikina and San Juan. These were revealed by the host-mediated assay. Chromosome breaking effects were observed in organic extracts of industrial areas in Cainta, Mandaluyong and Quezon City and also in commercial areas in Cainta, Mandaluyong, Pasig, Quezon City, and San Juan. The same observation was made of organic extracts from street soils of residential areas in Makati, Marikina and San Juan. These observations were correlated with benzo pyrene content of these street soil samples
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