A large acrocentric chromosome in the first pair of autosomes in natural populations of Mus musculus, Linne 1758

Stanimirovic, Z. . Department of Biology; Vucinic, M.; Soldatovic, B.; Vucicevic, M.

A large acrocentric chromosome in the first pair of autosomes in natural populations of Mus musculus, Linne 1758

1995

Stanimirovic, Z. (Faculty of Veterinary Medicine, Belgrade (Yugoslavia). Department of Biology) | Vucinic, M. | Soldatovic, B. | Vucicevic, M.

In this study, polymorphism of chromosomes was examined in natural populations of Mus musculus. The investigations were conducted in 5 different localities in North-West Serbia, around the rivers Sava nad Danube (Yugoslavia). Besides the frequent finding of Robertsonian type of chromosomal polymorphism, the presence of one large acrocentric chromosome in the first pair of autosome, unusual for the mouse karyotype, was observed in a large number of investigated animals. With appropriate cytogenetical methods, it was established that the altered chromosome had two additional insertions, located in regions 1C5 and 1R. From the results obtained for mouse karyotype tests and data from the literature, it could be concluded that the observed acrocentric chromosome resulted as an adaptation of mice to high quantity environmental pollutants in investigated localities.

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