Synergistic effect of antibiotics and oxytocin in the treatment of endometritis in mares
Ahmad, M. | Ahmad, N. | Mansoor, M.K. | Samad, H.A. (University of Agriculture, Faisalabad (Pakistan). Faculty of Veterinary Sciences)
The present study was designed to investigate the effect of oxytocin, with or without intrauterine antibiotics infusion, on conception rates in 150 endometritic mares. Uterine swabs were collected from each mare and processed for antibiotic sensitivity tests. Samples from 135 mares showing bacterial growth and antibiotic sensitivity were divided into following groups: Control, given oxytocin only, Gentamicin or gentamicin plus Oxytocin, Chloramphenicol or Chloramphenicol plus Oxytocin, Streptopenicillin plus Kanamycin or Streptopenicillin plus Kanamycin plus Oxytocin, and Norfloxacin or Norfloxacin plus Oxytocin. After treatment for five days, one heat was missed and on second heat mares were bred through natural mating and examined for pregnancy at least 60 days after service. The overall conception rate in mares of groups treated using antibiotics without oxytocin (62.22 %) was significantly higher (P less than 0.05) as compared to 40.00% in the control group. However, conception rates in mares of former groups did not differ from one another. Similarly, overall conception rate in mares treated using antibiotic plus oxytocin combination (82.62%) was significantly higher (P less than 0.05) than overall conception rate in mares treated with antibiotics alone (62.22%), or control (40.00%). It was concluded that oxytocin along with some suitable antibiotic (s) may be used for the treatment of endometritis and improvement of conception rates in endometritic mares.
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