The antimicrosporidial effect of albendazole in rabbits experimentally infected by Encephalitozoon cuniculi
2001
Neuschl, J. | Balent, P. | Stefkovic, M. | Levkutova, M. | Hipikova, V. | Saly, J. | Valencakova, A. (University of Veterinary Medicine, Kosice (Slovak Republic)) | Halanova, M.
The development of experimentally induced encephalitozoonosis (Encephalitozoon cuniculi) was observed in 12 adult female rabbits of the New Zealand white breed. Animals from the negative control group were not infected by microsporidia. Animals from the positive control group were infected by Encephalitozoon cuniculi microsporidia with a single intraperitoneal dose of 5.10E-7 per ml. Animals from the experimental group after inoculation with Encephalitozoon cuniculi in the same dose and way were subsequently administered albendazole - in the form of Aldifal 2.5% susp. a.u.v. (MEVAK - SR) in a dose 5 mg per kg of body weight (in a volume of 0.2 ml per os by a tube) from day 7 p.i., twice a week for 11 weeks and overall this was applied 21 times
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