Antioxidative Activities of Diarylheptanoids from Alnus japonica and their Structural relationship
2003
Lee, J.H. | Yeom, S.H. | Kim, M,K, | Kim, H.J. | Shim, J.G. | Lee, M.W. (Chung-Ang University, Seoul, Republic of Korea)
Antioxidative activities againt 1,1-dipheny1-2-picrylhydrazy1 (DPPH) radical were evaluated for ten diarylheptanoids, 1,7-bis-(3,4-dihydroxypheny1)-heptane-3-O-¥â-D-glucopyranosy(1¡æ3)-¥â-D-xylopyranoside(1), 1,7-bis-(3,4-dihydroxypheny1)-heptane-3-O-¥â-D-apiofuranosy1(1¡æ6)-¥â-D-glucopyranoside(2), 1,7-bis-(3,4-dihydroxypheny1)-heptane-5-O-¥â-D-glucopyranoside (3), 1,7-bis-(3,4-dihydroxypheny1)-5-hydroxyheptane(4), 1,7-bis-(3,4-dihydroxypheny1)-heptane-3-one-5-O-¥â-D-glucopyranoside(5), oregonin(6), hirautaonlo(7), hirsutenone(8), 1,7-bis-(3,4-dihydroxypheny1)-5-hydroxyheptane-3-O-¥â-D-xylopyranoside(9) and playphylloside(10), which were isolated from Alnus japonica, aglycones (4,7 and 8) and mono goycosides (3, 6 and 9) showed more strong antioxidative activities than diglycosides (1 and 2) against the DPPH radical. Especially, hirstutenone(8) showed superior activity among the diarylheptaoid.
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