Abnormal umbilical bleeding in a newborn Japanses black calf
2001
Kamimura, S. (Kagoshima Univ. (Japan). Faculty of Agriculture) | Tabata, K. | Yamamoto, N. | Ohishi, A. | Akuzawa, M.
Herniorrhaphy was used to treat a newborn Japanese Black calf with prolonged umbilical bleeding. Blood-chemistry analysis revealed large, granular, eosinophilic leukocytes and decreased platelet collagen-aggregation functions. Thromboelastography showed clotting time to be moderately prolonged in comparison with results for other cattle. Increased ocular-fundic red reflex was observed. Allele-specific PCR showed the sire and dam of the calf to be carriers of the Chediak-Higashi syndrome. The bleeding disorder was therefore diagnosed as Chediak-Higashi syndrome.
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