Changes in ECG QT interval in German Shepherd and Cocker Spaniel dogs during premedication and general anaesthesia | Elektrokardiogrammas QT intervala izmainas vacu aitu sunu un kokerspanielu skirnes dzivniekiem premedikacijas un visparejas anestezijas laika
2006
Avdosko, G., Latvia Univ. of Agriculture, Jelgava (Latvia). Faculty of Veterinary Medicine. Preclinical Inst. | Birgele, E., Latvia Univ. of Agriculture, Jelgava (Latvia). Faculty of Veterinary Medicine. Preclinical Inst.
The influence of premedication (atropine sulphate together with acepromazine maleate), followed by general anaesthesia (ketamine hydrochloride together with diazepam), on the dynamics (s) of QT interval in 34 German Shepherd and 32 Cocker Spaniel dogs was investigated using electrocardiographical lead II. Premedication drugs atropine sulphate and acepromazine maleate led to significant increase in ECG QT interval in dogs; the degree of increase was practically the same for both Cocker Spaniels and German Shepherds. The total effect of general anaesthetics (narcosis drugs) ketamine hydrochloride and diazepam administered after premedication was manifested in a significant decrease of QT interval in dogs. Cocker Spaniels and German Shepherds are characterized by a dramatic and significant decrease of QT interval one minute after administration of narcosis drugs. In Cocker Spaniels the decrease of QT interval due to the total effect of ketamine hydrochloride and diazepam continued up to the 30th minute of anaesthesia. Dynamics of QT interval in dogs due to the total effect of such anaesthetics as ketamine hydrochloride and diazepam at definite time points of anaesthesia is greatly dependant on the breed of the animal, but not on the gender. The dependence of changes in QT interval on animal breed should be taken into consideration in practical veterinary medicine when working with breed animals.
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