Phytochemical analyses and anti-microbial activities of the leaf and stem bark extracts of Garcinia kola - Herkel (family Gultiferae)
2004
Obuekwe, I.F. (Benin Univ. (Nigeria). Dept. of Pharmaceutical Microbiology) | Onwukaeme, N.D.
This study investigated the phytochemical constituents of the stem bark and leaves of Garcinia kola and evaluated the anti-microbial activities of their extracts on some human isolates from a reference hospital in Benin city, Nigeria. Results from the phytochemical analyses of the stem bark and leaves of Garcinia kola have revealed the presence of flavonoids, tannins and glycosides. Sapronins and alkaloids were detected only from the stem bark and the alkaloids were present in both the basic and salt forms. The microbiological evaluations of the stem bark extract showed that the aqueous extract only had inhibitory activity against Staphylococcus aureus at all concentrations used. For the leaf extract, the result only showed inhibitory activity on Staphylococcus aureus using methanolic solvents. The minimum inhibitory concentration of the extract on Staphylococcus aureus was 150mg/ml. Garcinia kola is well used in traditional medicine for various ailments and dis eases and can be very readily used in the treatment of diseases caused by Staphylococcus aureus.
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Эту запись предоставил National Agricultural Research Centre