Antioxidant and antibiotic activities of some seaweeds (Egyptian isolates)
2007
Shanab, S.M.M. (Cairo Univ. (Egypt). Botany Dept.)
Antioxidant activity was determined, by free radical scavenging (DPPH-decolorization method) and inhibition of lipid peroxidation (Fe2+/Ascorbate), in three species of seaweeds [Sargassum dentifolium, Laurencia papillosa & Jania corniculata (Egyptian isolates)]. The three species of seaweeds were collected from Defressoar (Suez Canal, Egypt) during spring 2004. Silymarin was used as a reference control in both assays. Algae were cleaned from epiphytes, washed, air-dried and powdered. Extraction of each algal species was carried out by aqueous ethanol or dichloromethane and different concentrations were prepared. Dichloromethane extract of each algal species demonstrated greater antioxidant activities than the ethanol extract using both bioassays. Maximum free radical scavenging activity was exhibited by higher concentration of dichloromethane extract of & dentifolium followed by L. papillosa and J. corniculata. Also, higher concentrati on of dichloromethane extract of L papillosa had the maximum anti-lipid peroxidation activity followed by S. dentifolium and J. corniculata. All extracts showed antibiotic activity against four bacterial and two fungal species. Spectrophotometric and chromatographic determination of the active compounds revealed that the antioxidant and antibiotic activities might be attributed to algal content of chlorophylls, carotenoids and free phenols as well as fatty acids.
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