Brine shirmp lethality activity of Thai medicinal plants in the Family Meliaceae
2004
Sirintorn Pisutthanan(Naresuan University, Phitsanulok (Thailand). Faculty of Pharmaceutical Sciences. Dept. of Pharmaceutical Chemistry and Pharmacognosy) | Pinyupa Plianbangchang(Naresuan University, Phitsanulok (Thailand). Faculty of Pharmaceutical Sciences. Dept. of Pharmacy Practice) | Nisit Pisutthanan(Naresuan University, Phitsanulok (Thailand). Faculty of Pharmaceutical Sciences. Dept. of Pharmaceutical Chemistry and Pharmacognosy) | Siruluk Ruanruay(Naresuan University, Phitsanulok (Thailand). Faculty of Pharmaceutical Sciences. Dept. of Pharmaceutical Chemistry and Pharmacognosy) | Onrudee Muanrit(Naresuan University, Phitsanulok (Thailand). Faculty of Pharmaceutical Sciences. Dept. of Pharmaceutical Chemistry and Pharmacognosy)
Brine shrimp larvae have been used as a bioassay for a variety of toxic substances. The method has been applied to plant extracts in order to facilitate the isolation of biologically active compounds. In this study, the plant in the family Meliaceae have been selected to test for brine shrimp lethality activity based on taxonomic approach including Azadirachta indica, Azadirachta indica var. siamensis, Melia azadarach, Sandoricum indicum and Swietenia macrophylla. The stem bark and leaf were separately collected and investigated for their activities. All of the stem bark extracts, except S. macrophylla, showed significant toxicity whereas all of the leaf extracts were inactive. The stem bark of Annona squamosa, which exhibited brine shrimp toxicity, has been used as positive control and its leaf and seed were also examined. The result showed that the leaf and seed of this plant exhibited higher potency than the stem bark.
Показать больше [+] Меньше [-]Ключевые слова АГРОВОК
Библиографическая информация
Эту запись предоставил Kasetsart University