Short term change of urinary N-acetyl-beta-D-glucosaminidase in reduced kidney mass with renal artery ligation
2006
Ebisawa, T.(Nihon Univ., Fujisawa, Kanagawa (Japan). Coll. of Bioresource Sciences) | Uechi, M. | Hori, Y. | Yamano, Y.
The aim of the present study was to evaluate short term urinary NAG levels in a model of reduced kidney mass. The half and quarter kidney mass were made from ligation of the renal artery. Both groups decreased in the level of excreted NAG on day 1 and 2 after operation. On day 5 after operation, both groups achieved urinary enzyme levels comparable to that of the sham-operated group. The remaining compensated nephrons held normal range of excreted urinary NAG levels, although reduced number of nephrons resulted in a decline in urinary NAG levels.
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