Elder ages decreases the susceptibility for Helicobacter pylori infection in an animal model
2007
Lee, J.U. (Seoul National University, Seoul, Republic of Korea) | Kim, S.H. (Seoul National University, Seoul, Republic of Korea) | Park, T.W. (Wonkwang University, Iksan, Republic of Korea) | Kim, O.J. (Wonkwang University, Iksan, Republic of Korea), E-mail: kimoj@wonkwang.ac.kr
Helicobacter pylori (H. pylori) is an important bacterial pathogen that causes chronic gastritis and is associated with gastroduodenal ulcer disease, adenocarcinoma of the distal stomach, and gastric lymphoma in humans. The differences of host susceptibility of H. pylori infection associated with host age have not been well-defined in human. To evaluate the difference in host susceptibility to infection in relation to age of acquisition of H. pylori infection, we designed an experiment involving inoculation of H. pylori ATCC 43504 at different ages of Mongolian gerbils.
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