Multicentric T cell lymphoma in a Maltese dog
2007
Jung, J.Y. (Cheju National University, Jeju, Republic of Korea) | Kang, S.C. (Cheju National University, Jeju, Republic of Korea) | Roh, I.S. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Sohn, H.J. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Yun, Y.M. (Cheju National University, Jeju, Republic of Korea) | Kim, J.H. (Cheju National University, Jeju, Republic of Korea) | Lee, K.K. (Cheju National University, Jeju, Republic of Korea) | An, M.C. (Halla Pet Hospital, Jeju, Republic of Korea) | Bae, J.H. (Cheju National University, Jeju, Republic of Korea) | Kim, J.H. (Cheju National University, Jeju, Republic of Korea), E-mail: kimjhoon@cheju.ac.kr
A case of multicentric high grade T cell lymphoma is reported in a 5-year-old male Maltese dog with generalized lymphadenopathy. The dog showed depression, anorexia, blindness, jaundice, arrhythmia, and hematuria for 8 months. Complete blood count and chemistry profile revealed anemia and increased alanine transferase, alkaline phosphatase, total bilirubin, and total cholesterol. Grossly, most of lymph nodes, spleen, and liver were enlarged and neoplastic masses were occupied in these tissues. Histologically, massive accumulation of small noncleaved neoplastic lymphocytes with high mitotic figures was observed in all lymph nodes and spleen.
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