[The integrated assessment of concentration of cholesterol and blood enzymic activity under non-histological diagnosis of hepatic dysfunction in high-producing cows with abomasum blockage]
2007
Bezborodov, P.N., Belgorod State Agricultural Academy (Russian Federation)
A simplified method is proposed to diagnose adipose degeneration of liver (ADL) based on measuring the concentration of cholesterol and serous activity of aspirate-amino transferase (AST) and gamma-glutamyl-dehydrogenase (GGT) and glutamyl-dehydrogenase (GLDH) in cows with left-handed (LAB) and right-handed abomasum blockage (RAB). A pre-operational examination of 23 lactating German Black-and-White cows has found 70% of animals with adipose degeneration confirmed by surgical treatment. The average level of cholesterol in blood serum in cows was lower than normal by 35%, with RAB – by 16.7% and equal in the control. A reduced concentration of cholesterol by 25% should be regarded as a threat of emerging hepatic dysfunction. The average level of serous activity of AST, GGT and GLDH in cows with ADL and LAB was: 209, 45.722 and 71.913 unit/l; with RAB – 248.333, 86.055 and 128.525 unit/l. The real influence of a type pf abomasum blockage on the serous activity was observed. In cows with LAB the enzymic activity of AST was twice higher, GGT – by 38% and GLDH – 5.1 times; in cows with RAB – 2.4, 2. 6 and 9.1 times, respectively. The average values of activity of AST, GGT and GLDH testifying to hepatic dysfunctions are 115, 33 and 27 units/l, respectively. The results obtained testify to activation of the hemogenic function of liver. It is recommended to perform palpation of liver as a prognostic ADL test besides biochemical blood tests during medical examination of cows; for diagnosis of LAB and RAB – to perform instrumental percussion in the region of 12-23 rib pairs of left abdominal wall and pressure percussion.
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