Cadmium-induced ovarian ultrastructure alterations in vivo and in vitro
2005
Massanyi, P.(Slovak Univ. of Agriculture in Nitra (Slovak Republic). Tr. A. Hlinku 2, 949 76 Nitra, Slovak Republic | Uhrin, V. | Kovacik, J.
The aim of this study was to determine effects of cadmium on the ultrastructure of various ovarian cells after an experimental administration. The structure of ovarian cells (granulosa, thecal, stromal, endothelial cells) was analyzed by transmission electron microscopy (TEM). In vivo -- animals (24) were divided into three groups (K, A, C). In group A (n=8) rabbits received cadmium i.p. (1.5 mg/kg body weight) and subsequently were killed 48 h after administration of cadmium. In group C (n=8) cadmium was administered at a dose of 1.0 mg/kg b.w. for 5 month in pelletized food. The last group (K) was the control, receiving no cadmium. In vitro ultrastructure of granulosa cells was studied after 48h of culture with (0.2, 10 and 20 ng CdCl2/ml) or without cadmium.
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Эту запись предоставил Slovak University of Agriculture in Nitra