Changes in the spinal trigeminal tract and its nucleus induced by spinal cord ischemia-reperfusion injury in dogs
Sulla, I.(University of Veterinary Medicine, Kosice (Slovak Republic))
In a group of nine adult mongrel dogs of both sexes weighing between 18 and 25 kilograms the authors have studied the possible connection between spinal cord and specific brain stem structures. In three animals(sham controls) they performed a left-sided thoracotomy only. In the six experimental animals they occluded the thoracic aorta by a tourniquet, approached through a left-sided thoracotomy, just distal to the origin of the left subclavian artery for thirty minutes. Procedures in control and experimental animals were performed with a general anaesthesia induced by pentobarbital(30 mg/kg i.v.)and maintained with a mixture of 1---2 % halothane with oxygen via an endotracheal cannula. On the sixth postoperative day all the dogs were killed by deep general anaesthesia (pentobarbital i.v. in a dose of 50 mg/kg) with a perfusion (3000 ml of saline) and fixation (the same volume of 10 % neutral formaldehyde). Thirty um thick sections from spinal cord and brain stem were cut by a microtome and processed according to the Nauta staining method. Light microscopic observations showed distinct changes in the spinal trigeminal tract, its nuclei and some ascending spinal systems originating in the lumbosacral and lower thoracic spinal cord segments. These projections are very probably related to the posterior spinocerebellar tract.
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Эту запись предоставил Slovak University of Agriculture in Nitra