Partial central diabetes inspidus in a rabbit
2009
Onuma, M.(Nihon Univ., Fujisawa, Kanagawa (Japan). Coll. of Bioresource Sciences) | Kondo, H. | Ishikawa, M. | Ono, S. | Ueki, M. | Ishida, T. | Shibuya, H. | Sato, T.
A 6-year-old neutered hybrid male rabbit (Oryctolagus cuniculus, weight: 1.28 kg) was brought into Onuma Animal Hospital with chief complaints of polyposia and polyuria. The volume of water intake was 760 (ml/head/day), six times greater than normal. The amount of urine production per day was 1.5 times larger than the normal value of 530 (ml/head/day). The urine specific gravity was low, at 1.001. After excluding several different diagnoses, the animal was diagnosed with partial diabetes insipidus based on the results of a modified water deprivation test. An intranasal synthetic vasopressin derivative was administered (1 drip, 24 hours), and the urine specific gravity, volume of water intake, and urinary production per day became 1.020 (median), 346 ml/head/day (median), and 200 ml/head/day (median), respectively. A diagnosis of partial central diabetes insipidus was consequently made.
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